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Z0153

Sigma-Aldrich

ZM 241385

≥98% (HPLC)

Synonim(y):

4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol

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About This Item

Wzór empiryczny (zapis Hilla):
C16H15N7O2
Numer CAS:
139180-30-6
Masa cząsteczkowa:
337.34
Numer MDL:
MFCD00908394
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
329831597
NACRES:
NA.77

Próba

≥98% (HPLC)

Postać

powder

kolor

white to tan

rozpuszczalność

DMSO: >15 mg/mL

temp. przechowywania

room temp

ciąg SMILES

Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4

InChI

1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)

Klucz InChI

PWTBZOIUWZOPFT-UHFFFAOYSA-N

Działania biochem./fizjol.

ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.

Cechy i korzyści

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Neurotoxicity research, 22(2), 150-157 (2012-03-13)
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