SAB4501670

Anti-Keratin 19 antibody produced in rabbit

affinity isolated antibody

• Synonim(y): CK-19, Cytokeratin-19, K19, KRT19, Keratin type I cytoskeletal 19
• Numer MDL: MFCD02263565
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: antigen 44 kDa
• reaktywność gatunkowa: mouse, human, rat
• stężenie: ~1 mg/mL
• metody: ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• numer dostępu NCBI: P08727
• numer dostępu UniProt: P08727
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... KRT19(3880)

Opis

Opis ogólny

Anti-Keratin 19 Antibody detects endogenous levels of total Keratin 19 protein.

Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein with a α-helical central domain. It belongs to the acidic type I cytokeratin family of proteins (KRTs). This gene is mapped to human chromosome 17q21.

Immunogen

The antiserum was produced against synthesized peptide derived from human Keratin 19.

Immunogen Range: 231-280

Działania biochem./fizjol.

Cytokeratin 19 (KRT19) plays a major role in structural rigidity and multipurpose scaffolds. Overexpression of this gene in various cancers may participate in tumorigenic transformation. It may modulate signaling pathways and mediate cell apoptosis, cell cycle arrest, invasion and metastasis. KRT19 plays a vital role in the cancer stemness of hepatocellular carcinoma (HCC).

Cechy i korzyści

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Postać fizyczna

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable