SAB4300230

Anti-phospho-EIF2AK2 (pThr⁴⁵¹) antibody produced in rabbit

affinity isolated antibody

• Synonim(y): Anti-EIF2AK1 antibody produced in rabbit, Anti-MGC126524 antibody produced in rabbit, Anti-PKR antibody produced in rabbit, Anti-PRKR antibody produced in rabbit, Anti-eukaryotic translation initiation factor 2-alpha kinase 2 antibody produced in rabbit
• Numer MDL: MFCD03455796
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: ~74 kDa
• reaktywność gatunkowa: human
• stężenie: 1 mg/mL
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• izotyp: IgG
• sekwencja immunogenna: (K-G-TP-L-R)
• numer dostępu NCBI: NP_001129123.1
• numer dostępu UniProt: P19525
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: phosphorylation (pThr451)
• informacje o genach: human ... EIF2AK2(5610)

Opis

Immunogen

Peptide sequence around phosphorylation site of threonine 451 (K-G-T(p)-L-R), according to the protein EIF2AK2.

Cechy i korzyści

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Opis wartości docelowych

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

Postać fizyczna

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable