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Key Documents

SAB4300102

Sigma-Aldrich

Anti-phospho-AKT2 (pSer474) antibody produced in rabbit

affinity isolated antibody

Synonim(y):

Anti-PKBB antibody produced in rabbit, Anti-PKBBETA antibody produced in rabbit, Anti-PRKBB antibody produced in rabbit, Anti-RAC-BETA antibody produced in rabbit, Anti-v-akt murine thymoma viral oncogene homolog 2 antibody produced in rabbit

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About This Item

Numer MDL:
Kod UNSPSC:
12352203
NACRES:
NA.41

pochodzenie biologiczne

rabbit

białko sprzężone

unconjugated

forma przeciwciała

affinity isolated antibody

rodzaj przeciwciała

primary antibodies

klon

polyclonal

Postać

buffered aqueous solution

masa cząsteczkowa

~60 kDa

reaktywność gatunkowa

human, rat, mouse

stężenie

1 mg/mL

metody

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

izotyp

IgG

sekwencja immunogenna

(Q-F-SP-Y-S)

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

wet ice

temp. przechowywania

−20°C

docelowa modyfikacja potranslacyjna

phosphorylation (pSer474)

informacje o genach

human ... AKT2(208)

Immunogen

Peptide sequence around phosphorylation site of serine 474 (Q-F-S(p)-Y-S), according to the protein AKT2.

Cechy i korzyści

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Opis wartości docelowych

General protein kinase capable of phosphorylating several known proteins.

Postać fizyczna

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Jinlong Zhao et al.
International journal of medical sciences, 15(10), 1062-1071 (2018-07-18)
Rac1, known as a "molecular switch", plays a crucial role in plenty of cellular processes. Rac1 aggravates the damage of myocardial cells in the process of myocardial ischemia-reperfusion during myocardial infarction through activating the NADPH oxidase and bringing about the
Victoria H Cruz et al.
Molecular metabolism, 16, 139-149 (2018-06-25)
TANK Binding Kinase 1 (TBK1) has been implicated in the regulation of metabolism through studies with the drug amlexanox, an inhibitor of the IκB kinase (IKK)-related kinases. Amlexanox induced weight loss, reduced fatty liver and insulin resistance in high fat
Zhenbing Lv et al.
Journal of translational medicine, 15(1), 257-257 (2017-12-21)
Metastasis is a major threat to colorectal cancer (CRC) patients. We have reported that peroxiredoxin-2 (PRDX2) is associated with CRC invasion and metastasis. However, the mechanisms regulating PRDX2 expression remain unclear. We investigate whether microRNAs (miRNAs) regulate PRDX2 expression in
Alberto Bavelloni et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(8), 9044-9061 (2019-05-17)
Murine thymoma viral oncogene homolog (AKT) kinases target both cytosolic and nuclear substrates for phosphorylation. Whereas the cytosolic substrates are known to be closely associated with the regulation of apoptosis and autophagy or metabolism and protein synthesis, the nuclear substrates
K Soukupová et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 52, 58-67 (2019-02-09)
The specific effects of sodium selenite (selenite) on a chemoresistant human bladder cancer cell line RT-112/D21 were investigated during 72 h. Selenite at low concentration of 2.5 μmol (otherwise tolerated in normal urothelial cells UROtsa) suppressed growth and proliferation of the tested

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