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Merck

RAB0259

Sigma-Aldrich

Human IL-15 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

Kod UNSPSC:
41116158
NACRES:
NA.32

reaktywność gatunkowa

human

opakowanie

kit of 96 wells (12 strips x 8 wells)

metody

ELISA: suitable
capture ELISA: suitable

moc wejściowa

sample type urine
sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3 pg/mL
standard curve range: 3.3-800 pg/mL

metoda wykrywania

colorimetric

Warunki transportu

wet ice

temp. przechowywania

−20°C

informacje o genach

human ... IL15(3600)

Opis ogólny

Interleukin-15 (IL-15) is a four α-helical bundle cytokine expressed in the immune system as well as in the skeletal muscles. The IL-15 gene is mapped to human chromosome 4q31.21.
The Human IL-15 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-15 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human IL-15

Zastosowanie

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Działania biochem./fizjol.

Interleukin-15 (IL-15) is an immunomodulatory cytokine, that plays a key role in the cluster of differentiation CD8+ T cell memory.. It plays a crucial role in the healing of chronic wounds. IL -15 has been implicated in the pathogenesis of autoimmune diseases.

Inne uwagi

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
This page may contain text that has been machine translated.

Elementy zestawu są też dostępne oddzielnie

Numer produktu
Opis
Karta charakterystyki

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)Karta charakterystyki

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)Karta charakterystyki

  • RABSTOP3ELISA Stop Solution (Item I)Karta charakterystyki

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)Karta charakterystyki

  • RABWASH420X Wash Buffer (Item B)Karta charakterystyki

Piktogramy

Corrosion

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Met. Corr. 1

Kod klasy składowania

8A - Combustible corrosive hazardous materials


Certyfikaty analizy (CoA)

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Krzysztof Ficek et al.
Frontiers in physiology, 10, 876-876 (2019-07-25)
Based on the important role of interleukin-15 (IL-15) in human metabolism and, in consequence, in body composition modulation, we examined whether rs1589241 and rs1057972 polymorphisms, analyzed individually or in combination, would influence the effects of a training program. Accordingly, we
Wei Fang et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 143(3), 335-343 (2006-02-04)
Interleukin-15 (IL-15) plays an important role in adaptive immune systems in vertebrates with similar bioactivities to interleukin-2 (IL-2). Here we report molecular cloning, sequence analysis and distribution of an IL-15 homologue from a pufferfish (Tetraodon nigroviridis). It is located within
A M Jones et al.
International journal of molecular medicine, 38(3), 679-686 (2016-07-28)
Chronic wounds represent a significant burden to health services and are associated with patient morbidity. Novel methods to diagnose and/or treat problematic wounds are needed. Interleukin (IL)-15 is a cytokine involved in a number of biological processes and disease states such
Thomas A Waldmann
Arthritis research & therapy, 6(4), 174-177 (2004-07-01)
Interleukin (IL)-15 is a dangerous inflammatory cytokine that induces tumor-necrosis factor-alpha, IL-1beta and inflammatory chemokines. It inhibits self-tolerance mediated by IL-2 mediated activation-induced cell death and facilitates maintenance of CD8+ memory T-cell survival including that of self-directed memory cells. Disordered
Pierfrancesco Marra et al.
Cancer research, 74(17), 4908-4921 (2014-07-02)
Despite its aggressive nature, triple-negative breast cancer (TNBC) often exhibits leucocyte infiltrations that correlate with favorable prognosis. In this study, we offer an explanation for this apparent conundrum by defining TNBC cell subsets that overexpress the IL15 immune receptor IL15RA.

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