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M2435

Sigma-Aldrich

c-Myc Peptide

≥97%, lyophilized powder

Synonim(y):

c-Myc tag

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About This Item

Numer MDL:
MFCD03456424
Kod UNSPSC:
12352202
NACRES:
NA.56

product name

c-Myc Peptide, lyophilized powder

pochodzenie biologiczne

synthetic

Poziom jakości

200

Próba

≥97%

Postać

lyophilized powder

masa cząsteczkowa

1203.3 Da

stężenie

5-10 μg/mL (Suggested working concentration to compete out the binding of c-Myc)

metody

protein extraction: suitable

temp. przechowywania

−20°C

Amino Acid Sequence

Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu

Opis ogólny

The c-Myc Peptide is a synthetic peptide with an amino acid sequence that corresponds to the amino acids 410-419 of the C-terminal of human c-myc.

Zastosowanie

Useful for displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific.

Inne uwagi

Amino acid sequence is corresponds to amino acids 410-419 of the C-terminal of human c-Myc.
Lyophilized from 0.1% TFA in H2O

Uwaga dotycząca przygotowania

Dissolve in water to a final concentration of 5 mg/mL.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

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Odwiedź Bibliotekę dokumentów

Yanxiao Zhang et al.
Oncotarget, 8(4), 5761-5773 (2016-12-23)
PAX8-PPARG fusion protein (PPFP) results from a t(2;3)(q13;p25) chromosomal translocation, is found in 30% of follicular thyroid carcinomas, and demonstrates oncogenic capacity in transgenic mice. A PPARG ligand, pioglitazone, is highly therapeutic in mice with PPFP thyroid cancer. However, only
Atanas G Atanasov et al.
Biochimica et biophysica acta, 1783(8), 1536-1543 (2008-04-03)
Hexose-6-phosphate dehydrogenase (H6PDH) has been shown to stimulate 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-dependent local regeneration of active glucocorticoids. Here, we show that coexpression with H6PDH results in a dramatic shift from 11beta-HSD1 oxidase to reductase activity without affecting the activity
Daria D Korotkova et al.
Cell reports, 29(4), 1027-1040 (2019-10-24)
The molecular basis of higher regenerative capacity of cold-blooded animals comparing to warm-blooded ones is poorly understood. Although this difference in regenerative capacities is commonly thought to be a result of restructuring of the same regulatory gene network, we hypothesized
Lian-Mei Tan et al.
The EMBO journal, 37(19) (2018-08-15)
In eukaryotes, heterochromatin regions are typically subjected to transcriptional silencing. DNA methylation has an important role in such silencing and has been studied extensively. However, little is known about how methylated heterochromatin regions are subjected to silencing. We conducted a
Advait Subramanian et al.
Cell, 176(6), 1461-1476 (2019-03-09)
Maintaining the optimal performance of cell processes and organelles is the task of auto-regulatory systems. Here we describe an auto-regulatory device that helps to maintain homeostasis of the endoplasmic reticulum (ER) by adjusting the secretory flux to the cargo load.
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