L9150

N-Lauroylsarcosine sodium salt

detergent for use in cell lysis

• Synonim(y): Sodium lauroyl sarcosinate, N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL
• Wzór liniowy: CH₃(CH₂)₁₀CON(CH₃)CH₂COONa
• Numer CAS: 137-16-6
• Masa cząsteczkowa: 293.38
• Beilstein: 5322974
• Numer WE: 205-281-5
• Numer MDL: MFCD00042728
• Kod UNSPSC: 12161902
• Identyfikator substancji w PubChem: 57654340
• NACRES: NA.52

Właściwości

• klasa czystości: for molecular biology
• Poziom jakości: 200
• opis: anionic
• linia produktu: BioReagent
• Próba: ≥94%
• Formularz: powder
• masa cząsteczkowa: micellar avg mol wt 600
• liczba agregacji: 2
• metody: protein purification: suitable; protein quantification: suitable
• CMC: 14.6 mM (20-25°C)
• rozpuszczalność: H₂O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
• obecność zanieczyszczeń: DNase, RNase, none detected
• temp. przechowywania: room temp
• ciąg SMILES: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
• InChI: 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
• Klucz InChI: KSAVQLQVUXSOCR-UHFFFAOYSA-M

Opis

Opis ogólny

Sodium lauroyl sarcosinate, the sodium salt of an acyl derivative of sarcosine—a natural amino acid occurring in muscles and body tissues—stands out as a valuable component in molecular biology, biochemical, and cell biology research. Derived from a natural fatty acid and the amino acid derivative sarcosine, N-Lauroylsarcosine is a biodegradable anionic surfactant usually synthesized through acylation and neutralization reactions involving lauric acid and sodium sarcosine.

This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry.

Zastosowanie

Suitable for

• solubilization and separation of membrane proteins
• lysis of cells during the isolation of RNA
• inhibition of hexokinase

Cechy i korzyści

• Suitable for Molecular Biology, Biochemical and Cell Biology research
• Can be used for Protein Purification and Quantification
• High purity product for research applications

Inne uwagi

Anionic surfactant.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS05
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H315,H318,H330
• Zwroty wskazujące środki ostrożności: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Kod klasy składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 512.6 °F - closed cup
• Temperatura zapłonu (°C): 267 °C - closed cup
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)