D6750

Sodium deoxycholate

≥97% (titration)

• Synonim(y): 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
• Wzór empiryczny (zapis Hilla): C₂₄H₃₉NaO₄
• Numer CAS: 302-95-4
• Masa cząsteczkowa: 414.55
• Beilstein: 3581950
• Numer WE: 206-132-7
• Numer MDL: MFCD00064139
• Kod UNSPSC: 12161900
• Identyfikator substancji w PubChem: 24894044
• NACRES: NA.21

Właściwości

• opis: anionic
• Poziom jakości: 200
• Próba: ≥97% (titration)
• Postać: powder
• masa cząsteczkowa: micellar avg mol wt 1200-5000
• liczba agregacji: 3-12
• CMC: 2-6 mM (20-25°C)
• rozpuszczalność: water: 50 mg/mL, clear, colorless to light yellow
• HLB: 16
• grupa funkcyjna: carboxylic acid
• Warunki transportu: ambient
• temp. przechowywania: room temp
• ciąg SMILES: [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
• Klucz InChI: FHHPUSMSKHSNKW-SMOYURAASA-M

Opis

Opis ogólny

Deoxycholic acid sodium salt, also known as Sodium Deoxycholate, is a highly versatile ionic detergent utilized for its exceptional ability to solubilize membrane-bound proteins and lyse cells. Its mechanism involves disrupting cell membranes and dissolving hydrophobic molecules, making it an invaluable reagent in scientific research applications. In protein research, it plays a pivotal role in solubilizing proteins, particularly those embedded in membranes, enabling their extraction, purification, and subsequent analysis.

Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.

Zastosowanie

Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue. It has been used in the decellularization of aortic valvular conduit.

Działania biochem./fizjol.

Solubilizes fats for absorption in the intestines.

Cechy i korzyści

Highly versatile surfactant for your cell biology and biochemical research

Inne uwagi

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H302
• Zwroty wskazujące środki ostrożności: P264 - P270 - P301 + P312 - P501
• Klasyfikacja zagrożeń: Acute Tox. 4 Oral
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves