Przejdź do zawartości
Merck
Wszystkie zdjęcia(1)

Kluczowe dokumenty

I3901

Sigma-Aldrich

IL-1α rat

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonim(y):

Czynnik aktywujący limfocyty, Interleukina-1α, rIL-1α

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
Wszystkie zdjęcia(1)

About This Item

Numer MDL:
MFCD01635091
Kod UNSPSC:
12352202
NACRES:
NA.77

Nazwa produktu

Interleukin-1α from rat, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

pochodzenie biologiczne

rat

Poziom jakości

100

rekombinowane

expressed in E. coli

Próba

≥97% (SDS-PAGE)

Formularz

lyophilized powder

siła działania

1-10 pg/mL ED50

jakość

endotoxin tested

masa cząsteczkowa

~18 kDa

opakowanie

pkg of 5 μg

metody

cell culture | mammalian: suitable

zanieczyszczenia

≤0.1 EU/μg

numer dostępu UniProt

P16598

temp. przechowywania

−20°C

informacje o genach

rat ... Il1a(24493)

Działania biochem./fizjol.

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LA F), activates T cells and lymphocytes, which then proliferate and secrete Interleukin-2 (IL-2). The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.

Postać fizyczna

Lyophilized from 0.2 μm filtered phosphate buffered saline containing 0.25 mg of bovine serum albumin.

Komentarz do analizy

The biological activity of recombinant rat IL-1α was measured by its ability to stimulate cell proliferation using a mouse helper T cell line, D10.G4.1.
Ta strona może zawierać tekst przetłumaczony maszynowo.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
MKCR0785
MKCP7084
MKCN8870
MKCL5321
MKCG3572

Nie widzisz odpowiedniej wersji?

Jeśli potrzebujesz konkretnej wersji, możesz wyszukać konkretny certyfikat według numeru partii lub serii.

Wyszukaj dokument COA

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Xuankang Wang et al.
Journal of neuroinflammation, 18(1), 256-256 (2021-11-07)
Neurotoxic microglia and astrocytes begin to activate and participate in pathological processes after spinal cord injury (SCI), subsequently causing severe secondary damage and affecting tissue repair. We have previously reported that photobiomodulation (PBM) can promote functional recovery by reducing neuroinflammation
T Nishida et al.
Journal of biochemistry, 105(3), 351-357 (1989-03-01)
A cDNA sequence coding for rat interleukin-1 alpha (IL-1 alpha) has been isolated from a cDNA library that was prepared with mRNA derived from LPS-stimulated rat peritoneal macrophages by using human IL-1 alpha cDNA as a probe. The rat cDNA
Aybike Saglam et al.
Glia, 69(4), 1022-1036 (2020-12-15)
Astrocytes are key players in CNS neuroinflammation and neuroregeneration that may help or hinder recovery, depending on the context of the injury. Although pro-inflammatory factors that promote astrocyte-mediated neurotoxicity have been shown to be secreted by reactive microglia, anti-inflammatory factors
Lilianne Barbar et al.
STAR protocols, 1(3), 100172-100172 (2020-12-31)
Given the critical roles of astrocytes in neuroinflammation and neurological diseases, models for studying human astrocyte biology are in increasing demand. Here, we present a protocol to isolate human astrocytes from induced pluripotent stem cell (iPSC)-based cultures, neural organoids, and
Kevin A Guttenplan et al.
Cell reports, 31(12), 107776-107776 (2020-06-25)
Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells (RGCs) in the retina, often as a result of prolonged increases in intraocular pressure. We show that preventing the formation of neuroinflammatory reactive astrocytes prevents the death

Produkty

Interleukin Family (IL)

The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and may induce anti-tumor immunity.

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej