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Merck

I3650

Sigma-Aldrich

Interleukin-4 from rat

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)

Synonim(y):

rIL-4, IL-4

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About This Item

Numer MDL:
Kod UNSPSC:
12352202
NACRES:
NA.32

pochodzenie biologiczne

rat

Poziom jakości

rekombinowane

expressed in E. coli

Próba

≥97% (SDS-PAGE)

Postać

lyophilized powder

masa cząsteczkowa

predicted mol wt 13.5 kDa

opakowanie

pkg of 5 μg

metody

cell culture | mammalian: suitable

zanieczyszczenia

endotoxin, tested

numer dostępu UniProt

temp. przechowywania

−20°C

informacje o genach

rat ... Il4(287287)

Działania biochem./fizjol.

Interleukin-4 is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and bFGF-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.
Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific.

Postać fizyczna

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Komentarz do analizy

The biological activity of recombinant rat IL-4 was measured by its ability to stimulate proliferation of rat splenocytes.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Robert Nunan et al.
Glia, 62(8), 1313-1327 (2014-05-08)
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Jeremy A Daniel et al.
The Journal of cell biology, 183(5), 777-783 (2008-12-03)
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PloS one, 9(10), e109146-e109146 (2014-10-03)
It has been shown that Faecalibacterium prausnitzii (F. prausnitzii), one of the dominant intestinal bacterial flora, may protect colonic mucosa against the development of inflammation and subsequent inflammatory bowel disease (IBD), with the underlying mechanisms being unclear. The impacts of
Alberto Purwada et al.
Biomaterials, 63, 24-34 (2015-06-16)
Ex vivo engineered three-dimensional organotypic cultures have enabled the real-time study and control of biological functioning of mammalian tissues. Organs of broad interest where its architectural, cellular, and molecular complexity has prevented progress in ex vivo engineering are the secondary immune organs.
Rebecca Winkelmann et al.
PloS one, 9(5), e97953-e97953 (2014-05-31)
Maturation as well as antigen-dependent activation of B cells is accompanied by alternating phases of proliferation and quiescence. We and others have previously shown that Krüppel-like factor 2 (KLF2), a regulator of T cell quiescence and migration, is upregulated in

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