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I3525

Sigma-Aldrich

Interleukin-17A human

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonim(y):

CTLA-8, IL-17

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About This Item

Numer MDL:
MFCD01094096
Kod UNSPSC:
12352202
NACRES:
NA.32

pochodzenie biologiczne

human

Poziom jakości

100

rekombinowane

expressed in E. coli

Próba

≥98% (SDS-PAGE)

Postać

lyophilized powder

siła działania

≤2.0 ng/mL ED50

masa cząsteczkowa

31 kDa

opakowanie

pkg of 50 μg

metody

cell culture | mammalian: suitable

zanieczyszczenia

endotoxin, tested (endotoxin level is less than 0.1 ng per μg cytokine (1 EU/μg).)

numer dostępu UniProt

Q16552

temp. przechowywania

−20°C

informacje o genach

human ... IL17A(3605)

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Działania biochem./fizjol.

IL-17, initially known as CTLA-8, is a T cell-expressed polypeptide that appears to be involved in the regulation of the hematopoietic system. IL-17 has been shown to induce IL-6, IL-8, and G-CSF production by fibroblasts; all of these cytokines have demonstrated effects on hematopoiesis.

Postać fizyczna

Lyophilized with no additives.

Komentarz do analizy

  • The biological activity of human IL-17 is measured by its ability to induce IL-6 production using NHDF cells.
  • Biological activity is also determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblast. The expected ED50 is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

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