H7250

Histamine dihydrochloride

≥99% (TLC), powder, endogenous histamine receptor agonist

• Synonim(y): 2-(4-Imidazolyl)ethylamine dihydrochloride
• Wzór empiryczny (zapis Hilla): C₅H₉N₃ · 2HCl
• Numer CAS: 56-92-8
• Masa cząsteczkowa: 184.07
• Beilstein: 3624116
• Numer WE: 200-298-4
• Numer MDL: MFCD00012703
• Kod UNSPSC: 12352116
• eCl@ss: 32160406
• Identyfikator substancji w PubChem: 24277777
• NACRES: NA.77

Właściwości

• product name: Histamine dihydrochloride, ≥99% (TLC), powder
• Próba: ≥99% (TLC)
• Postać: powder
• kolor: white to off-white
• mp: 249-252 °C (lit.)
• temp. przechowywania: 2-8°C
• ciąg SMILES: Cl[H].Cl[H].NCCc1c[nH]cn1
• InChI: 1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
• Klucz InChI: PPZMYIBUHIPZOS-UHFFFAOYSA-N
• informacje o genach: human ... HRH1(3269) , HRH2(3274)

Opis

Opis ogólny

Histamine dihydrochloride is a derivative of histamine. It prevents the formation of ROS (reactive oxygen species), which inhibits the activation of T cells and natural killer cells. Histamine dihydrochloride is implicated in tumor cell apoptosis. It prevents the relapse of acute myeloid leukemia in patients.

Zastosowanie

Histamine dihydrochloride has been used:

• as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)
• to determine its level in fish using HPLC (high performance liquid chromatography)
• to assess the tracheal response to antigens in guinea-pigs

Cechy i korzyści

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H315,H317,H319,H334,H335
• Zwroty wskazujące środki ostrożności: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organy docelowe: Respiratory system
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Faceshields, Gloves