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Key Documents

F8065

Sigma-Aldrich

Fucoidan from Macrocystis pyrifera

≥85%

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About This Item

Numer CAS:
Kod UNSPSC:
12352201
NACRES:
NA.25

pochodzenie biologiczne

algae (Macrocystis pyrifera)

Poziom jakości

Próba

≥85%

Postać

powder

kolor

white to brown

working range

4-7

rozpuszczalność

water: 10 mg/mL, clear to hazy, colorless to very faintly brown

temp. przechowywania

room temp

Opis ogólny

Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.

Działania biochem./fizjol.

Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation which subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.

Inne uwagi

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Odwiedź Bibliotekę dokumentów

Anna Pielesz et al.
The Analyst, 140(13), 4599-4607 (2015-06-02)
Differential scanning calorimetry (DSC) and thermogravimetric (TGA) investigations, acetate electrophoresis (CAE), Fourier-transform infrared spectrometry (FTIR), scanning electron microscopy (SEM) analysis and microbiological procedures were all carried out after heating the samples to a temperature sufficient for simulating a burn incident.
Wentong Cui et al.
Laboratory investigation; a journal of technical methods and pathology, 94(4), 382-393 (2014-03-13)
Endothelial dysfunction, characterized by impairment of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) bioavailability, has been implicated in diabetic cardiovascular pathogenesis. In this study, low-molecular-weight fucoidan (LMWF), which has multiple biological activities including anti-inflammatory and anti-oxidative properties, was
Xiang Li et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1661-1667 (2014-06-07)
Nuclear imaging of active plaques still remains challenging. Advanced atherosclerotic plaques have a strong expression of P-selectin by the endothelium overlying active atherosclerotic plaques, but not on the endothelium overlying inactive fibrous plaques. We proposed a new approach for noninvasive
Yuangang Liu et al.
Journal of nanoscience and nanotechnology, 14(5), 3844-3849 (2014-04-17)
Fucoidan was chosen a substitute for alginate in chitosan-based polyelectrolytes or polyiones because it is negatively charged and possesses pharmacological properties. The fucoidan-chitosan nanospheres were prepared by the sonification method, and different formulation variables were investigated to get regular and
G Heim et al.
The British journal of nutrition, 111(9), 1577-1585 (2014-02-08)
In the present study, two experiments were conducted to (1) evaluate the effect of laminarin and/or fucoidan on ileal morphology, nutrient transporter gene expression and coefficient of total tract apparent digestibility (CTTAD) of nutrients and (2) determine whether laminarin inclusion

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