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Key Documents

F8315

Sigma-Aldrich

Fucoidan from Undaria pinnatifida

≥95%

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About This Item

Numer CAS:
Kod UNSPSC:
12352201
NACRES:
NA.25

pochodzenie biologiczne

algae (Undaria pinnatifida)

Poziom jakości

Próba

≥95%

Postać

powder

kolor

white to off-white

przydatny zakres pH

3.0 -7.0

rozpuszczalność

water: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow

temp. przechowywania

room temp

Opis ogólny

Fucoidan has a complex chemical composition. It contains mannose, galactose, glucose, xylose and other monosaccharides. It is also composed of uronic acids, acetyl groups and protein.
Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.

Zastosowanie

Fucoidan from Undaria pinnatifida has been used to assess its antimicrobial potential in vitro.

Działania biochem./fizjol.

Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation which subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.

Inne uwagi

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Fucoidan: structure and bioactivity
Li B, et al.
Molecules (Basel), 13(8), 1671-1695 (2008)
Arumugam Ponnan et al.
Environmental science and pollution research international, 27(25), 31760-31766 (2020-06-07)
Fucoidan is a unique bioactive and dietary polymer enriched mainly in the cell wall matrix of the brown seaweeds. This present study was intended to reveal the antigenotoxicity effect of fucoidan on 4-nitroquinolin-1-oxide (4-NQO) induced genetics damage and apoptosis in
Anna Pielesz et al.
The Analyst, 140(13), 4599-4607 (2015-06-02)
Differential scanning calorimetry (DSC) and thermogravimetric (TGA) investigations, acetate electrophoresis (CAE), Fourier-transform infrared spectrometry (FTIR), scanning electron microscopy (SEM) analysis and microbiological procedures were all carried out after heating the samples to a temperature sufficient for simulating a burn incident.
Wentong Cui et al.
Laboratory investigation; a journal of technical methods and pathology, 94(4), 382-393 (2014-03-13)
Endothelial dysfunction, characterized by impairment of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) bioavailability, has been implicated in diabetic cardiovascular pathogenesis. In this study, low-molecular-weight fucoidan (LMWF), which has multiple biological activities including anti-inflammatory and anti-oxidative properties, was
Xiang Li et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1661-1667 (2014-06-07)
Nuclear imaging of active plaques still remains challenging. Advanced atherosclerotic plaques have a strong expression of P-selectin by the endothelium overlying active atherosclerotic plaques, but not on the endothelium overlying inactive fibrous plaques. We proposed a new approach for noninvasive

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