E4644

Anti-Erythropoietin Receptor antibody produced in goat

affinity isolated antibody

• Synonim(y): Anti-EPO R, Anti-EPO Receptor
• Kod UNSPSC: 51111800
• Identyfikator substancji w PubChem: 24894570
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: goat
• Poziom jakości: 100
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• reaktywność gatunkowa: human
• metody: western blot: 1 μg/mL
• numer dostępu UniProt: P19235
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• ciąg SMILES: CCCCCCCC/C=C/CCCCCCCCCC(OC(CCCCCCCC/C=C/CCCCCCCCC)=O)=O
• InChI: 1S/C40H74O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(41)43-40(42)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17,19-20,22H,3-16,18,21,23-38H2,1-2H3/b19-17+,22-20+
• Klucz InChI: WOPZJDCVLPFUEY-ZEYSCXRRSA-N
• informacje o genach: human ... EPOR(2057)

Opis

Opis ogólny

Erythropoietin Receptor (EPO R) is a protein that belongs to type I cytokine receptor superfamily and is expressed mainly in megakaryocytes, erythoid progenitors, endothelial cells and neurons. Erythropoietin binds to EPO receptor and stimulates Jak2 tyrosine kinase which in turn phosphorylate tyrosine residue of EPO receptor and results in activation of several intracellular pathways (Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors). Anti-Erythropoietin Receptor antibody can be used for analyzing the neurite outgrowth. Goat anti-Erythropoietin Receptor antibody reacts specifically with recombinant human erythropoietin receptor.

Immunogen

recombinant human erythropoietin soluble receptor, expressed in NSO cells.

Zastosowanie

Anti-Erythropoietin Receptor can be used in western blotting at a working antibody concentration of 1 μg/ml for detecting human EPO receptor.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Postać fizyczna

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 13 - Non Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable