C7688
Chaperonin 60 from Escherichia coli
>95% (SDS-PAGE), recombinant, expressed in E. coli overproducing strain, lyophilized powder
Synonim(y):
Cpn60, GroEL
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About This Item
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pochodzenie biologiczne
Escherichia coli
Poziom jakości
rekombinowane
expressed in E. coli overproducing strain
Próba
>95% (SDS-PAGE)
Formularz
lyophilized powder
metody
electron microscopy: suitable
mass spectrometry (MS): suitable
przydatność
passes test (Refolding (w/GroES))
numer dostępu UniProt
temp. przechowywania
2-8°C
informacje o genach
human ... HSPD1(3329)
Opis ogólny
Research area: Cell Signaling
Chaperonin 60 (GroEL) and chaperonin 10 (GroES) belong to the ubiquitous family of heat-shock molecular chaperones found in prokaryotes and in eukaryotic organelles.
Chaperonin 60 (GroEL) and chaperonin 10 (GroES) belong to the ubiquitous family of heat-shock molecular chaperones found in prokaryotes and in eukaryotic organelles.
Zastosowanie
Chaperonin 60 from Escherichia coli has been used:
- in mass spectroscopy
- in cryo-electron microscopy imaging as control for testing particle distribution
- as standard in infrared spectrum measurements
- as a protein sample for stability assessment and characterization studies using differential mobility analysis (DMA) and cryo-electron microscopy (cryo-EM).
Działania biochem./fizjol.
Apart from its role in facilitating protein folding, chaperonin 60 (Cpn60) serves as an extracellular signaling protein, showing functional similarities to certain proinflammatory cytokines. Furthermore, Cpn60 contributes to the inhibition of lipid accumulation and adipogenesis during the initial stages of cellular differentiation, thereby exerting anti-obesity effects.
Opakowanie
Package size based on protein content.
Postać fizyczna
Lyophilized powder containing Tris buffer salts, potassium chloride, magnesium chloride, dithiothreitol, and trehalose as stabilizer.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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