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C5851
CGP 35348 hydrate
≥97% (NMR), solid
Synonim(y):
(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate
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About This Item
Wzór empiryczny (zapis Hilla):
C8H20NO4P · xH2O
Numer CAS:
Masa cząsteczkowa:
225.22 (anhydrous basis)
Numer MDL:
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
NACRES:
NA.77
Polecane produkty
Próba
≥97% (NMR)
Formularz
solid
warunki przechowywania
desiccated
kolor
white
rozpuszczalność
H2O: >20 mg/mL
inicjator
Novartis
temp. przechowywania
−20°C
ciąg SMILES
O.CCOC(OCC)P(O)(=O)CCCN
InChI
1S/C8H20NO4P.H2O/c1-3-12-8(13-4-2)14(10,11)7-5-6-9;/h8H,3-7,9H2,1-2H3,(H,10,11);1H2
Klucz InChI
SRBHGEXMDCJOMS-UHFFFAOYSA-N
Zastosowanie
CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABAB) receptor inhibitor:
- to study its effects on intrinsic optical signal (IOS) in rat hippocampus
- alone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of rat
- to study its effects on hepatocellular carcinoma cells (HCC)
Działania biochem./fizjol.
CGP 35348 is a γ-aminobutyric acid-B (GABAB) receptor antagonist. It has a higher affinity towards post-versus presynaptic receptors that can penetrate the blood-brain barrier.
Cechy i korzyści
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Przestroga
Product is hygroscopic
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
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