A9519

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate

≥98% (TLC), suitable for ligand binding assays

• Synonim(y): Adjuvant Peptide, Muramyl dipeptide
• Wzór empiryczny (zapis Hilla): C₁₉H₃₂N₄O₁₁ · xH₂O
• Numer CAS: 53678-77-6
• Masa cząsteczkowa: 492.48 (anhydrous basis)
• Beilstein: 4220745
• Numer WE: 258-696-9
• Numer MDL: MFCD00077638
• Kod UNSPSC: 12352209
• Identyfikator substancji w PubChem: 24891464
• NACRES: NA.26

Właściwości

• product name: N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate, ≥98% (TLC)
• Poziom jakości: 200
• Próba: ≥98% (TLC)
• Postać: powder
• metody: ligand binding assay: suitable
• kolor: white
• Zastosowanie: cell analysis
• temp. przechowywania: −20°C
• ciąg SMILES: C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O
• InChI: 1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19?/m0/s1
• Klucz InChI: BSOQXXWZTUDTEL-QAQREVAFSA-N

Opis

Amino Acid Sequence

MurNAc-Ala-Agn

Zastosowanie

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.

Działania biochem./fizjol.

Enhances antigenicity of weak antigens, increasing antibody titer.

Muramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.

N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP, muramyl dipeptide), a neurotrophic and immunomodulatory factor related to bacterial peptidoglycans, is used as an immune modulation factor that enhances immune response and to study neural development.

Opakowanie

Bottomless glass bottle. Contents are inside inserted fused cone.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)