387R-1

Olig2 (EP112) Rabbit Monoclonal Primary Antibody

• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: culture supernatant
• rodzaj przeciwciała: primary antibodies
• klon: EP112, monoclonal
• opis: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: bottle of 1.0 mL predilute (387R-17); bottle of 7.0 mL predilute (387R-18); vial of 0.1 mL concentrate (387R-14); vial of 0.5 mL concentrate (387R-15); vial of 1.0 mL concentrate (387R-16)
• producent / nazwa handlowa: Cell Marque^™
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• izotyp: IgG
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• informacje o genach: human ... OLIG2(10215)

Opis

Opis ogólny

Olig2, a basic helix–loop–helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas.^1-2 More than half of glioblastomas are weakly positive for Olig2. No Olig2 expression has been found in the non-glial tumors including neuroepithelial tumors, ependymomas, subependymomas, medulloblastomas, and nonneuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and haemangioblastomas.^1-2 In order to characterize cellular subtypes that constitute astrocytomas, oligoastrocytomas and oligodendrogliomas, double labeling of Olig2 and GFAP has been performed which identified two phenotypically distinct tumor populations. The first is Olig2+/GFAP– which has an oligodendroglial morphology, corresponding to pure oligodendrogliomas that contain only oligodendroglial cells; the second is Olig2–/GFAP+ which has an astrocytic phenotype, including not only oligoastrocytomas, but also WHO astrocytomas.^1-2

Jakość

IVD

IVD

IVD

RUO

Powiązanie

Olig2 Positive Control Slides, Product No. 387S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Uwaga dotycząca przygotowania

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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