268R-1

IgD (EP173) Rabbit Monoclonal Primary Antibody

• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: culture supernatant
• rodzaj przeciwciała: primary antibodies
• klon: EP173, monoclonal
• opis: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: bottle of 1.0 mL predilute (268R-17); bottle of 7.0 mL predilute (268R-18); vial of 0.1 mL concentrate (268R-14); vial of 0.5 mL concentrate (268R-15); vial of 1.0 mL concentrate (268R-16)
• producent / nazwa handlowa: Cell Marque^®
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• izotyp: IgG
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C

Opis

Opis ogólny

The monoclonal antibody against IgD reacts with immunoglobin D delta chains. In tonsil and lymph node, immunohistochemical staining for IgD immunoglobulin heavy chain is usually used to highlight the tonsil and nodal architecture since the IgD antibody stains mantle zone cells in secondary follicles and mantle cells in primary follicles.¹ It has been reported that IgD can be detected in the surface/cytoplasm of neoplastic cells of common small B lymphoid cell lymphomas, such as small lymphocytic lymphoma, mantle cell lymphoma, marginal zone lymphoma (especially splenic marginal zone lymphoma), and follicular lymphoma.^1-2 IgD expression in L & P cells of nodular lymphocyte predominant Hodkin lymphoma has been seen in subsets of cases (27% to 71.4%).^1-3 The IgD positive L & P cells are usually located in the extrafollicular area with a relatively T-cell-rich background^1,3 IgD expression is rarely seen in T-cell rich B-cell lymphoma. Studies have demonstrated that Reed-Sternberg cells of classic Hodgkin lymphoma were negative for IgD^1,3 IgD multiple myeloma is a rare bone marrow plasma cell dyscrasia and can be identified by the IgD antibody, especially when a dry tap is encountered.⁴

Jakość

IVD

IVD

IVD

RUO

Powiązanie

IgD Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Uwaga dotycząca przygotowania

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable