12247

Oleuropein

≥98.0%

• Synonim(y): (2S,3E,4S)-3-Ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester
• Wzór empiryczny (zapis Hilla): C₂₅H₃₂O₁₃
• Numer CAS: 32619-42-4
• Masa cząsteczkowa: 540.51
• Numer WE: 251-129-6
• Numer MDL: MFCD16879008
• Kod UNSPSC: 12352202
• Identyfikator substancji w PubChem: 329749662
• NACRES: NA.32

Właściwości

• Poziom jakości: 100
• Próba: ≥98.0%
• zanieczyszczenia: ≤5.0% water
• Zastosowanie: metabolomics; vitamins, nutraceuticals, and natural products
• ciąg SMILES: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3
• InChI: 1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
• Klucz InChI: RFWGABANNQMHMZ-ZCHJGGQASA-N

Opis

Opis ogólny

Oleuropein is the major secondary metabolite found in the olive leaf extract. It is a secoiridoid polyphenol with a structure comprising of a glycosylated ester of elenolic acid with hydroxytyrosol.

Zastosowanie

Oleuropein has been used:

• as an anti-inflammatory and antioxidant agent in hepatic steatosis on high-fat diet (HFD) fed mice
• to evaluate protective effects and antioxidant properties on male reproductive function in mice
• to study its inhibitory effects on bacterial (E. coli) ATP synthase
• as an inhibitor of plasminogen activator inhibitor-1 (PAI-1) to test its effect on the proliferation of breast cancer cells

Działania biochem./fizjol.

Oleuropein has anti-cancer, antimicrobial, antiviral, anti-ischemic and hypolipidemic activities. It functions as a skin protectant and aids anti-aging. Oleuropein is also implicated in anti-platelet aggregation, hypotensive, anti-rheumatic, antipyretic, diuretic and vasodilatory effects. It reduces the risk of coronary artery diseases. Oleuropein has been shown to augment the secretion of noradrenaline and adrenaline in rat.

Opakowanie

Bottomless glass bottle. Contents are inside inserted fused cone.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable