113R-2

CD13 (EP117) Rabbit Monoclonal Primary Antibody

• Synonim(y): Aminopeptidase-N
• Kod UNSPSC: 12352203

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: culture supernatant
• rodzaj przeciwciała: primary antibodies
• klon: EP117, monoclonal
• opis: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: vial of 0.1 mL concentrate (113R-24); vial of 0.1 mL concentrate Research Use Only (113R-24-RUO); vial of 0.5 mL concentrate (113R-25); vial of 1.0 mL concentrate (113R-26); vial of 1.0 mL concentrate Research Use Only (113R-26-RUO); vial of 1.0 mL pre-dilute Research Use Only (113R-27-RUO); vial of 1.0 mL pre-dilute ready-to-use (113R-27); vial of 7.0 mL pre-dilute ready-to-use (113R-28); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (113R-28-RUO)
• producent / nazwa handlowa: Cell Marque^™
• stężenie: 0.1-5 μg/mL (predilute); 2.5-125 μg/mL (concentrate)
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• izotyp: IgG
• kontrola: liver
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• wizualizacja: cytoplasmic, membranous
• informacje o genach: human ... ANPEP(290)

Opis

Opis ogólny

CD13 (aminopeptidase-N) is a transmembrane protease present in many tissues and cell types (e.g., endothelial and epithelial cells, fibroblasts, and leukocytes). CD13 is expressed in various solid and hematological malignancies in humans and is useful in identifying acute myeloid leukemia when used in a panel including antibodies against CD13(+), CD34(+), CD117(+), CD16(-), and CD33(+). This protein is also expressed in myeloid sarcoma and anti-CD13 is useful in its identification using a panel.

In addition, it has been reported that CD13 is expressed in both normal and neoplastic liver tissue, where it exhibits a canalicular distribution pattern similar to that seen for polyclonal CEA and CD10. Thus, anti-CD13 can be useful as an additional marker in differentiating between HCC and non-hepatocellular neoplasms.

Jakość

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Powiązanie

CD13 Positive Control Slides, Product No. 113S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

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Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable