ANPEP
alanyl (membrane) aminopeptidase
Synonyms:
APN, CD13, GP150, LAP1, P150, PEPN
Species:
Human ANPEP (290), Mouse Anpep (16790), Rat Anpep (81641), chicken ANPEP (395667), domestic cat ANPEP (493785), Horse ANPEP (100050397), cow ANPEP (404191), dog ANPEP (403913), sheep ANPEP (101104860), Domestic Rabbit ANPEP (100009167) ...More
UniProtKB ID:
Gene ID:
- Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
- Mouse(16790) alanyl (membrane) aminopeptidase
- Rat(81641) alanyl (membrane) aminopeptidase
- chicken(395667) alanyl (membrane) aminopeptidase
- domestic cat(493785) alanyl (membrane) aminopeptidase
- Horse(100050397) alanyl (membrane) aminopeptidase
- cow(404191) alanyl (membrane) aminopeptidase
- dog(403913) alanyl (membrane) aminopeptidase
- sheep(101104860) alanyl (membrane) aminopeptidase
- Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
- domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
- naked mole-rat(101706035) alanyl (membrane) aminopeptidase
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD13 Rabbit Monoclonal Antibody, clone RM403, affinity purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Milli-Mark® Anti-CD13-FITC Antibody, clone WM-47, clone WM-47, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry
Anti-APN/CD13 Antibody, clone DF-5, clone DF-5, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-Aminopeptidase N/CD13 Antibody, clone BR2, clone BR2, from mouse,
Species Reactivity
human
Application
ELISA
affinity chromatography
electron microscopy
flow cytometry
immunoprecipitation (IP)
affinity chromatography
electron microscopy
flow cytometry
immunoprecipitation (IP)
Anti-CD13 antibody, Rabbit monoclonal, clone SP182, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human, pig, rabbit
Application
flow cytometry
immunohistochemistry
immunohistochemistry