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G0355000

Glutamic acid

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

L-Glutamic acid, (S)-2-Aminopentanedioic acid, Glu

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About This Item

Wzór liniowy:
HO2CCH2CH2CH(NH2)CO2H
Numer CAS:
56-86-0
Masa cząsteczkowa:
147.13
Beilstein:
1723801
Numer MDL:
MFCD00002634
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329799811
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

glutamic acid

producent / nazwa handlowa

EDQM

mp

205 °C (dec.) (lit.)

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

2-8°C

ciąg SMILES

N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

Klucz InChI

WHUUTDBJXJRKMK-VKHMYHEASA-N

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Glutamic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Działania biochem./fizjol.

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumenty section.

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Kwas (S)-(+)-glutaminowy for synthesis

Sigma-Aldrich

8.16004

Kwas (S)-(+)-glutaminowy

Kwas L-glutaminowy for biochemistry

Millipore

1.00291

Kwas L-glutaminowy

Glutaminian sodu United States Pharmacopeia (USP) Reference Standard

USP

1446600

Glutaminian sodu

L-Glutamic acid hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1294987

L-Glutamic acid hydrochloride

Dania Vecchia et al.
Neurobiology of disease, 69, 225-234 (2014-06-08)
Familial hemiplegic migraine type 1 (FHM1), a monogenic subtype of migraine with aura, is caused by gain-of-function mutations in CaV2.1 (P/Q-type) calcium channels. In FHM1 knockin mice, excitatory neurotransmission at cortical pyramidal cell synapses is enhanced, but inhibitory neurotransmission at
R Dave et al.
Amino acids, 24(3), 245-261 (2003-04-23)
Gamma-fluorinated analogues of glutamic acid and glutamine are compounds of biological interest. Syntheses of such compounds are extensively reviewed in this article. 4-fluoroglutamic acid was prepared as a mixture of racemic diastereomers by Michael reaction, inverse-Michael reaction or by electrophilic
Miquel Bosch et al.
Neuron, 82(2), 444-459 (2014-04-20)
Synapses store information by long-lasting modifications of their structure and molecular composition, but the precise chronology of these changes has not been studied at single-synapse resolution in real time. Here we describe the spatiotemporal reorganization of postsynaptic substructures during long-term
Daniel Meyer et al.
Neuron, 82(2), 430-443 (2014-04-20)
Subsynaptic structures such as bouton, active zone, postsynaptic density (PSD) and dendritic spine, are highly correlated in their dimensions and also correlate with synapse strength. Why this is so and how such correlations are maintained during synaptic plasticity remains poorly
Ulrike Pannasch et al.
Nature neuroscience, 17(4), 549-558 (2014-03-04)
Astrocytes play active roles in brain physiology by dynamic interactions with neurons. Connexin 30, one of the two main astroglial gap-junction subunits, is thought to be involved in behavioral and basic cognitive processes. However, the underlying cellular and molecular mechanisms
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Protokoły

GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

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