D1435

Dimethyl sulfoxide

meets EP testing specifications, meets USP testing specifications

• Synonim(y): DMSO
• Wzór liniowy: (CH₃)₂SO
• Numer CAS: 67-68-5
• Masa cząsteczkowa: 78.13
• Beilstein: 506008
• Numer WE: 200-664-3
• Numer MDL: MFCD00002089
• Kod UNSPSC: 12191502
• Identyfikator substancji w PubChem: 57654071
• NACRES: NA.71

Właściwości

• agency: meets EP testing specifications; meets USP testing specifications
• Poziom jakości: 200
• gęstość pary: 2.7 (vs air)
• ciśnienie pary: 0.42 mmHg ( 20 °C)
• Próba: ≥99.5%
• Postać: liquid
• temp. samozapłonu: 573 °F
• granice wybuchowości: 42 %, 63 °F
• metody: cryopreservation: suitable
• zanieczyszczenia: ≤0.1% water (Karl Fischer, USP); ≤0.2% water (Karl Fischer, EP)
• kolor: colorless
• współczynnik refrakcji: n20/D 1.478-1.479; n20/D 1.479 (lit.)
• tw: 189 °C (lit.)
• mp: 16-19 °C (lit.)
• rozpuszczalność: H₂O: miscible (completely)
• gęstość: 1.100-1.104 g/mL at 25 °C (relative density (EP)); 1.10 g/mL (lit.)
• absorpcja UV: λ: 285 nm A_max: ≤0.20; λ: 295 nm A_max: ≤0.20
• ciąg SMILES: CS(C)=O
• InChI: 1S/C2H6OS/c1-4(2)3/h1-2H3
• Klucz InChI: IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Opis

Zastosowanie

Dimethyl sulfoxide has been used:

• for the dissolution of tetramethylrhodamine dye, which is used as fluorophore for fluorescence in- situ hybridization (FISH) experiments
• as a control in indirect immunofluorescent assay (IFA) of swine testicular (ST) cells
• for the suspension and separation of buccal cells
• a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs.

Działania biochem./fizjol.

Dimethyl sulfoxide (DMSO) is a low molecular weight, less hydrophilic and a freely permeable cryoprotectant. It is a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant and vitrification agent for the preservation of cells, tissues and organs.

Przestroga

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Inne uwagi

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 188.6 °F - closed cup
• Temperatura zapłonu (°C): 87 °C - closed cup
• Środki ochrony indywidualnej: Eyeshields, Gloves, type ABEK (EN14387) respirator filter