1.37117

Dimethyl sulfoxide

EMPROVE^® EXPERT, Ph. Eur., ChP, USP

• Synonim(y): Methanesulfinylmethane, Methyl sulfoxide, Dimethyl(oxido)sulfur, DMSO, DMSO
• Wzór liniowy: (CH₃)₂SO
• Numer CAS: 67-68-5
• Masa cząsteczkowa: 78.13
• Beilstein: 506008
• Numer MDL: MFCD00002089
• Kod UNSPSC: 12352119
• Numer indeksu EC: 200-664-3

Właściwości

• agency: ChP; Ph. Eur.; USP
• Poziom jakości: 500
• gęstość pary: 2.7 (vs air)
• ciśnienie pary: 0.42 mmHg ( 20 °C)
• linia produktu: EMPROVE^® EXPERT
• Próba: ≥99.9% (GC)
• Postać: liquid
• temp. samozapłonu: 573 °F
• granice wybuchowości: 42 %, 63 °F
• metody: API processing | polymorph screening: suitable
• współczynnik refrakcji: n20/D 1.479 (lit.)
• kinematic viscosity: 2.14 cSt
• tw: 189 °C (lit.)
• mp: 16-19 °C (lit.)
• temp. przejścia: flash point 87 °C
• gęstość: 1.10 g/mL (lit.)
• Zastosowanie: liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical; semi-solid formulation
• temp. przechowywania: 2-30°C
• ciąg SMILES: CS(C)=O
• InChI: 1S/C2H6OS/c1-4(2)3/h1-2H3
• Klucz InChI: IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Opis

Opis ogólny

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Zastosowanie

Dimethyl sulfoxide is used as penetration enhancer in topical formulation, as cryopreservative in cell therapy and solvent in antibody drug conjugate production.
Due to its low microbial and endotoxin limits, Dimethyl Sulfoxide Emprove^® Expert is especially suitable for high-risk applications.

Przestroga

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Charakterystyka techniczna

8.0 g/m3 (20 °C)

Informacje prawne

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 188.6 °F - closed cup
• Temperatura zapłonu (°C): 87 °C - closed cup