C2150000

Cholecalciferol for system suitability

European Pharmacopoeia (EP) Reference Standard

• Synonim(y): Cholecalciferol, (+)-Vitamin D₃, 7-Dehydrocholesterol activated, Activated 7-dehydrocholesterol, Calciol
• Wzór empiryczny (zapis Hilla): C₂₇H₄₄O
• Numer CAS: 67-97-0
• Masa cząsteczkowa: 384.64
• Beilstein: 2339331
• Numer MDL: MFCD00078131
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329774967
• NACRES: NA.24

Właściwości

• pochodzenie biologiczne: synthetic
• klasa czystości: pharmaceutical primary standard
• agency: EP
• rodzina API: cholecalciferol
• Formularz: solid
• producent / nazwa handlowa: EDQM
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp: 83-86 °C (lit.)
• Zastosowanie: pharmaceutical (small molecule)
• Format: neat
• temp. przechowywania: −20°C
• ciąg SMILES: CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
• InChI: 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
• Klucz InChI: QYSXJUFSXHHAJI-YRZJJWOYSA-N
• informacje o genach: human ... VDR(7421)

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Cholecalciferol, also referred to as vitamin D₃, promotes the absorption of calcium and phosphorus in the body to regulate bone growth. It is most commonly found in humans and animals and is produced in our skin when exposed to sunlight. It is used to treat and prevent bone disorders (such as rickets, osteomalacia).

Zastosowanie

Cholecalciferol for system suitability may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

Działania biochem./fizjol.

Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.

Vitamin D acts through a receptor that modulates the proliferation and differentiation of both normal and cancer cells.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H300 + H310 + H330,H372
• Zwroty wskazujące środki ostrożności: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
• Klasyfikacja zagrożeń: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral
• Kod klasy składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable