90210

D-(+)-Trehalose dihydrate

suitable for microbiology, ≥99.0%, composed of two α-glucose units that is used as a protectant, stabilizer and to support proper folding

• Synonim(y): Trehalose dihydrate, a-d-glucopyranosyl-a-d-glucopyranoside, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
• Wzór empiryczny (zapis Hilla): C₁₂H₂₂O₁₁ · 2H₂O
• Numer CAS: 6138-23-4
• Masa cząsteczkowa: 378.33
• Beilstein: 5322018
• Numer WE: 202-739-6
• Numer MDL: MFCD00071594
• Kod UNSPSC: 41106212
• Identyfikator substancji w PubChem: 329769859
• NACRES: NA.85

Właściwości

• Poziom jakości: 200
• Próba: ≥99.0% (HPLC); ≥99.0%
• Formularz: powder
• aktywność optyczna: [α]20/D +176 to +186°, c = 2% in H₂O
• masa cząsteczkowa: 378.33 g/mol
• zanieczyszczenia: ≤0.1% glucose
• pozostałość po prażeniu: ≤0.1% (as SO₄)
• rozpuszczalność: H₂O: 0.1 g/mL, clear, colorless
• ślady anionów: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• ślady kationów: As: ≤0.1 mg/kg; Ca: ≤200 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤10 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤10 mg/kg
• Zastosowanie: microbiology
• ciąg SMILES: [H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
• Klucz InChI: DPVHGFAJLZWDOC-PVXXTIHASA-N

Opis

Opis ogólny

D-(+)-Trehalose is a disaccharide composed of two α-glucose units. It is used as a cryoprotectant in a variety of cell freezing media. Used as a protectant in transportation media. It predominantly exists among the species that support anhydrobiosis (life without water). It serves as a carbohydrate reserve in microorganisms and protects them from adverse conditions, such as heat, cold, dehydration, desiccation, and oxidation. Trehalose acts as a chemical chaperone affecting protein folding. It is known to prevent the generation of amyloids and accumulation of β-amyloid in vitro. A similar effect of trehalose has been observed with Huntingtin protein aggregation. Thus, it might serve as a protective agent in Alzheimer′s disease and Huntington′s disease. Trehalose stimulates the better initial growth of Salmonella cells.

Zastosowanie

D-(+)-Trehalose can be used as a carbohydrate reserve in certain cell cultures to tide over environmental stresses. It can also be used in biopharmaceutical monoclonal antibody formulations and as a protein stabilizer.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)