MAGPMAG-24K

MILLIPLEX^® Mouse Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay

for the simultaneous quantification of multiple analytes

• Kod UNSPSC: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Właściwości

• Poziom jakości: 200
• reaktywność gatunkowa: mouse
• producent / nazwa handlowa: Milliplex^®
• assay range: accuracy: 90-104%; standard curve range: 1-1,000 pg/mL; (Endothelin-1); standard curve range: 137-100,000 pg/mL; (Follistatin); standard curve range: 137-100,000 pg/mL; (HGF); standard curve range: 137-100,000 pg/mL; (SDF-1); standard curve range: 14-10,000 pg/mL; (IL-1b); standard curve range: 14-10,000 pg/mL; (Leptin); standard curve range: 14-10,000 pg/mL; (MIP-1α); standard curve range: 14-10,000 pg/mL; (sALK-1); standard curve range: 14-10,000 pg/mL; (sCD31/ PECAM-1); standard curve range: 27-20,000 pg/mL; (Angiopoietin-2); standard curve range: 27-20,000 pg/mL; (EGF); standard curve range: 27-20,000 pg/mL; (Endoglin); standard curve range: 27-20,000 pg/mL; (MCP-1); standard curve range: 27-20,000 pg/mL; (VEGF-C); standard curve range: 3-2,000 pg/mL; (PLGF-2); standard curve range: 6-4,000 pg/mL; (TNFα); standard curve range: 6-4,000 pg/mL; (VEGF-A); standard curve range: 69-50,000 pg/mL; (FGF-2/FGF-basic); standard curve range: 69-50,000 pg/mL; (Prolactin); standard curve range: 69-50,000 pg/mL; (VEGF-D); standard curve range: 69-50,000 pg/mL; (sFasL); standard curve range: 7-5,000 pg/mL; (Amphiregulin); standard curve range: 7-5,000 pg/mL; (Betacellulin); standard curve range: 7-5,000 pg/mL; (G-CSF); standard curve range: 7-5,000 pg/mL; (IL-17A); standard curve range: 7-5,000 pg/mL; (IL-6); standard curve range: 7-5,000 pg/mL; (KC/CXCL1)
• metody: multiplexing: suitable
• metoda wykrywania: fluorometric (Luminex xMAP)
• Warunki transportu: wet ice

Opis

Opis ogólny

Angiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient, or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration, and cancer. Angiogenesis plays a significant role in tumor growth and metastasis.

MILLIPLEX^® Mouse Angiogenesis//Growth Factor Panel, is a 24-plex (for serum/plasma) or 27-plex (for cell culture) kit to be used for the simultaneous quantification of the following analytes: Angiopoietin-2, G-CSF, sFasL, sAlk-1, Amphiregulin, Leptin, IL-1b, Betacellulin, EGF, IL-6, Endoglin, Endothelin-1, FGF-2, Follistatin, HGF, PECAM-1, IL-17, PLGF-2, KC, MCP-1, Prolactin, MIP-1a, SDF-1, VEGF-C, VEGF-D, VEGF-A, and TNFα. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

Specyficzność

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Zastosowanie

• Analytes: sALK-1, Amphiregulin, Angiopoietin-2, Betacellulin, sCD31/sPECAM-1, EGF, Endoglin, Endothelin-1, sFasL, FGF-2 (FGF-basic), Follistatin (FST), G-CSF, HGF, IL-1β, IL-6, IL-17A (CTLA8), KC (GRO/CINC-1/CXCL1), Leptin, MCP-1 (CCL2), MIP-1α (CCL3), Placental Growth Factor 2 (PLGF-2), Prolactin, SDF-1 (CXCL12), TNF-α, VEGF-A, VEGF-C, VEGF-D
• NOTE: Angiopoeitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples
• Recommended Sample Type: Mouse serum, plasma or tissue/cell culture supernatants or lysates
• Recommended Sample Dilution: 25 μL per well of diluted serum or plasma; cell/tissue culture samples may require diltion in appropriate control medium
• Assay Run Time: Overnight (16-20 hours) at 2-8°C
• Research Category: Cancer

Cechy i korzyści

Design your multiplex kit by choosing available analytes within this panel.

Opakowanie

Everything you need in a single kit.

Przechowywanie i stabilność

Recommended storage for kit components is 2 - 8°C.

Inne uwagi

Please note: Sample Type must be selected when configuring this kit. Angiopoeitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples.

Sensitivity: Refer to kit protocol for sensitivities of individual analytes.

Informacje prawne

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

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• Zwroty wskazujące rodzaj zagrożenia: H302 + H312 + H332,H317,H318,H373,H411
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• Kod klasy składowania: 10 - Combustible liquids