MABN501

Anti-SUR1 Antibody, clone N289/16

clone N289/16, from mouse

• Synonim(y): ATP-binding cassette sub-family C member 8, Sulfonylurea receptor 1
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: N289/16, monoclonal
• reaktywność gatunkowa: human, mouse
• reaktywność gatunkowa (przewidywana na podstawie homologii): rat (immunogen homology)
• metody: immunohistochemistry: suitable; western blot: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_037171
• numer dostępu UniProt: Q09429
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... ABCC8(6833)

Opis

Opis ogólny

Sulfonylurea receptor 1 (SUR1) is also called ATP-binding cassette sub-family C member 8, and is a member of the ABC transporter superfamily. SUR1 is a putative subunit of the beta-cell ATP-sensitive potassium channel (KATP) and functions as a regulator of ATP-sensitive K+ channels and insulin release.

Specyficzność

This antibody recognizes the C-terminus of SUR1. Representative lot deteted Sur1 in crude brain membrane preparations
in SUR1 wild-type (WT) mouse cell lysate, and demonstrated a loss of signal in SUR1 knockout (KO) mouse cell lysate (Prof. J. Trimmer, University of California, Davis.).

Immunogen

Recombinant protein corresponding to the C-terminus of rat SUR1.

Zastosowanie

Anti-SUR1 Antibody, clone N289/16 is a highly specific mouse monoclonal antibody, that targets SUR & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SUR1 in human thalamus tissue.

Jakość

Evaluated by Western Blotting in mouse hypothalamus tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SUR1 in 10 µg of mouse hypothalamus tissue lysate.

Opis wartości docelowych

~ 180 kDa observed

Postać fizyczna

Format: Purified

Komentarz do analizy

Control
Mouse hypothalamus tissue lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable