MABN139

Anti-mGluR5 Antibody, clone 11D9.1

clone 11D9.1, from mouse

• Synonim(y): Metabotropic glutamate receptor 5, mGluR5
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: 11D9.1, monoclonal
• reaktywność gatunkowa: human, rat
• metody: immunohistochemistry: suitable; western blot: suitable
• izotyp: IgG2bκ
• numer dostępu NCBI: NP_000833
• numer dostępu UniProt: P41594
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... GRM5(2915)

Opis

Opis ogólny

Metabotropic glutamate receptor 5 (mGluR5) is a member of the G-protein coupled receptor family and functions as a receptor for glutamate. mGluR5 activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.

Immunogen

GST-tagged recombinant protein corresponding to human mGluR5.

Zastosowanie

Detect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected mGluR5 in normal human brain tissue.

Jakość

Evaluated by Western Blotting in rat brain micropreparation tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected mGluR5 in 10 µg of rat brain micropreparation tissue lysate. The lysate was not boiled during preperation for western blotting.

Opis wartości docelowych

~150 kDa observed. The calculated molecular weight is 130 kDa, however mGluR5 has been shown as a ~150 kDa band in western blots (Romano, C., et al. (1996). J Biol Chem. 271(45):28612-28616).

Postać fizyczna

Format: Purified

Komentarz do analizy

Control
Rat brain micropreparation tissue lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable