MAB3786

Anti-APC Antibody, CT, clone C-APC 28.9

clone C-APC 28.9, Chemicon^®, from mouse

• Synonim(y): Adenomatous Polyposis Coli Protein
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: C-APC 28.9, monoclonal
• reaktywność gatunkowa: human, mouse
• opakowanie: antibody small pack of 25 μg
• producent / nazwa handlowa: Chemicon^®
• metody: immunofluorescence: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NM_000038.3
• numer dostępu UniProt: P25054
• Warunki transportu: ambient
• temp. przechowywania: 2-8°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... APC(324) ; mouse ... Apc(11789)

Opis

Opis ogólny

The adenomatous polyposis coli tumor suppressor gene is mutated (often deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and over 80% of colorectal cancers. C-APC 28.8 can be used for APC expression and detection of APC mutations.

Specyficzność

Recognizes human APC, molecular weight is approximately 310kDa.

Immunogen

Epitope: C-terminus

Human APC C-terminal fusion with MBP (maltose binding protein).

Zastosowanie

Anti-APC Antibody, C-terminus, clone C-APC 28.9 is a Mouse Monoclonal Antibody for detection of APC also known as Adenomatous Polyposis Coli Protein & has been validated in IF, IP, WB & IHC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

Western blot

Immunohistochemistry (Frozen sections)

Immunofluorescence

Immunoprecipitation

Optimal working dilutions must be determined by end user.

Jakość

Tested

Postać fizyczna

Format: Purified

Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.

Przechowywanie i stabilność

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

Komentarz do analizy

Control
POSITIVE CONTROL: colon cell line HCT116

Inne uwagi

feature_concentration_valuePlease refer to lot specific datasheet.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable