MAB2300
Milli-Mark® Pan Neuronal Marker
Milli-Mark Pan Neuronal Marker is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC, IF & IHC.
Synonim(y):
Marker neuronów
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
mouse
Poziom jakości
forma przeciwciała
purified antibody
klon
monoclonal
reaktywność gatunkowa
rat, mouse, human
producent / nazwa handlowa
Neuro-Chrom
metody
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
izotyp
IgG1
Warunki transportu
wet ice
docelowa modyfikacja potranslacyjna
unmodified
Opis ogólny
Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a monoclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse fixations, cell culture and immunohistochemistry protocols, including archival brain tissue, giving researchers a convienent and specific qualitative and quantitative tool for studying neuronal morphology.
Specyficzność
Cat. # MAB2300 is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
Reactivity with other species has not been determined.
Immunogen
Epitope: Whole Neuron Marker
Zastosowanie
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Jakość
Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry.
Postać fizyczna
Blended monoclonal antibody cocktail in PBS with 0.05% NaN3
Format: Purified
Przechowywanie i stabilność
Maintain at 2-8°C for up to 1 year from date of receipt.
Komentarz do analizy
Control
Rat E18 cortex primary neurons
Rat E18 cortex primary neurons
Informacje prawne
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Harald Lund et al.
Nature immunology, 19(5), 1-7 (2018-04-18)
The cytokine transforming growth factor-β (TGF-β) regulates the development and homeostasis of several tissue-resident macrophage populations, including microglia. TGF-β is not critical for microglia survival but is required for the maintenance of the microglia-specific homeostatic gene signature1,2. Under defined host
Short-term fasting induces profound neuronal autophagy.
Alirezaei, M; Kemball, CC; Flynn, CT; Wood, MR; Whitton, JL; Kiosses, WB
Autophagy null
Erdinç Dursun et al.
PloS one, 12(11), e0188605-e0188605 (2017-11-28)
Our recent study indicated that vitamin D and its receptors are important parts of the amyloid processing pathway in neurons. Yet the role of vitamin D receptor (VDR) in amyloid pathogenesis is complex and all regulations over the production of
Pankaj Patyal et al.
Neurochemical research, 45(3), 663-671 (2019-11-30)
The myelin proteolipid protein gene (PLP1) encodes the most abundant protein in CNS myelin. Expression of the gene must be strictly regulated, as evidenced by human X-linked leukodystrophies resulting from variations in PLP1 copy number, including elevated dosages as well
Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by ?7 nicotinic receptor agonist.
Narla, ST; Klejbor, I; Birkaya, B; Lee, YW; Morys, J; Stachowiak, EK; Prokop et al.
Stem Cells Translational Medicine null
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