ABT148

Anti-Claudin-11 Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): Claudin-11, Oligodendrocyte-specific protein
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: human
• reaktywność gatunkowa (przewidywana na podstawie homologii): chimpanzee (based on 100% sequence homology)
• metody: western blot: suitable
• numer dostępu NCBI: NP_005593
• numer dostępu UniProt: O75508
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... CLDN11(5010)

Opis

Opis ogólny

Claudin-11 (CLDN11; or Oligodendrocyte-specific protein) is expressed in Sertoli cells of the testis. It is involved in the formation of tight junctions, which is required for spermatogenesis. Previous studies have indicated that claudin-11 may prevent the progression of bladder cancer by blocking cell invasion and metastatis.

Specyficzność

Other homologies: Mouse and Rat (93% sequence homology).

This antibody recognizes the cytoplasmic domain of Claudin-11.

Immunogen

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.

Zastosowanie

Anti-Claudin-11 Antibody is an antibody against Claudin-11 for use in Western Blotting.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Western Blot Analysis: 1 µg/mL from a representative lot detected Claudin-11 in human kidney tissue lysate.

Western Blot Analysis: 2 µg/mL from a representative lot detected Claudin-11 in human testis tissue lysate.

Jakość

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Claudin-11 in 10 µg of human brain tissue lysate.

Opis wartości docelowych

~22 kDa observed. An uncharacterized band may be observed at ~60 kDa in some tissue lysates.

Postać fizyczna

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
Human brain tissue lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable