9310-OP

TRIS Hydrochloride

OmniPur^® Grade, >=99.0%

• Synonim(y): Trizma^® hydrochloride, Trizma, Tris(hydroxymethyl)aminomethane, TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethane hydrochloride
• Wzór liniowy: NH₂C(CH₂OH)₃ · HCl
• Numer CAS: 1185-53-1
• Masa cząsteczkowa: 157.60
• Beilstein: 3675235
• Numer MDL: MFCD00012590
• Kod UNSPSC: 12161700
• NACRES: NA.25

Właściwości

• Poziom jakości: 100
• Formularz: crystalline powder; needles
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• kolor: white
• przydatny zakres pH: 7.0-9.0
• pKa (25°C): 8.1
• Warunki transportu: ambient
• ciąg SMILES: Cl.NC(CO)(CO)CO
• InChI: 1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
• Klucz InChI: QKNYBSVHEMOAJP-UHFFFAOYSA-N

Opis

Opis ogólny

Molecular Biology Grade.
260 (10%, water): ≤0.05 AU
A₂₈₀ (10%, water): ≤0.05 AU
Assay: ≥99%
DNAse: none detected
Identity IR spectrum: conforms
Lead (Pb): ≤.0002%
Phosphatase: none detected
Protease: none detected
RNAse: none detected
Water (H₂O): ≤0.5%





Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Zastosowanie

• Use of tetraethylammonium (TEA) and Tris loading for blocking TRPM7 channels in intact cells.: This study highlights the application of TRIS Hydrochloride in blocking TRPM7 channels, which is significant for cell signaling and ion channel regulation in pharmacological research (Holderby & Kozak, 2024).


• Investigating the influence of solvent type and pH on protein adsorption onto silica surface by evanescent-wave cavity ring-down spectroscopy.: This study uses TRIS Hydrochloride to explore protein-silica interactions, providing insights into surface chemistry and biomolecular adsorption processes (Alnaanah & Mendes, 2024).

Ostrzeżenie

Toxicity: Irritant (B)

Inne uwagi

The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable