8.51029

N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms)

Novabiochem^®

• Synonim(y): N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms), O-(N-Biotinyl-3-aminopropyl)-O′-(N-glutaryl-3-aminopropyl)-diethyleneglycol · DIPEA
• Wzór empiryczny (zapis Hilla): C₂₅H₄₄N₄O₈S · xC₈H₁₉N
• Numer CAS: 1205744-09-7
• Masa cząsteczkowa: 560.70
• Kod UNSPSC: 12352106

Właściwości

• Poziom jakości: 200
• linia produktu: Novabiochem^®
• Próba: ≥95.0% (HPLC); ≥98% (TLC)
• Postać: powder
• przydatność reakcji: reaction type: Biotinylations
• producent / nazwa handlowa: Novabiochem^®
• mp: 131-136 °C
• Zastosowanie: peptide synthesis
• temp. przechowywania: 2-8°C

Opis

Opis ogólny

The use of this novel biotin derivative incorporates a hydrophilic 20 atom PEG spacer between the peptide and biotin. This not only greatly improves the solubility of the resultant peptide, but reduces steric hindrance between the peptide and biotin, leading to better avidin binding and higher biological activity. The biotin-PEG derivative can be easily incorporated using any standard coupling method as the final step in SPPS, immediately prior to cleavage of the peptide from the resin.

Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis

Powiązanie

Replaces: 01-63-0133

Komentarz do analizy

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (50 mg in 1 ml NMP): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informacje prawne

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable