8.20122

Benzamidine hydrochloride hydrate

for synthesis

• Synonim(y): Benzamidine hydrochloride hydrate
• Wzór empiryczny (zapis Hilla): C₇H₈N₂ · xHCl · yH₂O
• Numer CAS: 206752-36-5
• Masa cząsteczkowa: 120.15 (anhydrous free base basis)
• Numer MDL: MFCD00066285
• Kod UNSPSC: 12352107
• Numer indeksu EC: 216-795-4
• NACRES: NA.22

Właściwości

• Poziom jakości: 200
• Próba: ≥98.5% (HPLC)
• Postać: powder
• pH: 5 (20 °C, 50 g/L in H₂O)
• mp: 80-84 °C
• temp. przechowywania: 2-30°C
• InChI: 1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)/p+1
• Klucz InChI: PXXJHWLDUBFPOL-UHFFFAOYSA-O

Opis

Zastosowanie

• Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes.: This study investigates the interaction of benzamidine hydrochloride hydrate as a serine protease inhibitor, focusing on its binding mechanism in the presence of water molecules. Utilizing neutron crystallography, the research provides insights into the dynamic role of water in enhancing the binding affinity and stability of the inhibitor to trypsin. This understanding is crucial for the design of more effective protease inhibitors in pharmaceutical applications (Schiebel et al., 2018).

Komentarz do analizy

Assay (HPLC, area%): ≥ 98.5 % (a/a)
Water (K. F.): 7.0 - 13.0 %
Identity (IR): passes test

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable