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580549

Millipore

Tauroursodeoxycholic Acid, Sodium Salt

Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.

Synonim(y):

Tauroursodeoxycholic Acid, Sodium Salt, Sodium Tauroursodeoxycholate

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About This Item

Wzór empiryczny (zapis Hilla):
C26H44NO6S · Na
Numer CAS:
35807-85-3
Masa cząsteczkowa:
521.69
Kod UNSPSC:
12352106
NACRES:
NA.21

Poziom jakości

100

Próba

≥97% (TLC)

Postać

solid

producent / nazwa handlowa

Calbiochem®

warunki przechowywania

OK to freeze

kolor

white

rozpuszczalność

water: 100 mg/mL

Warunki transportu

ambient

temp. przechowywania

15-25°C

InChI

1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20?,21?,22+,24?,25+,26-/m1/s1

Klucz InChI

BHTRKEVKTKCXOH-AYSJQVDDSA-N

Powiązane kategorie

Opis ogólny

Detergent useful for the solubilization of lipids and membrane–bound proteins.
Detergent useful for the solubilization of lipids and membrane-bound proteins. Has cryoprotective effects against hydrophobic bile salts in rats. Also reported to inhibit pepsin activity in vitro.

Zastosowanie


  • Inhibition of endoplasmic reticulum stress combined with activation of angiotensin-converting enzyme 2: novel approach for the prevention of endothelial dysfunction in type 1 diabetic rats.: This study highlights the efficacy of tauroursodeoxycholic acid, sodium salt in reducing endoplasmic reticulum stress, suggesting its utility in preventing vascular complications in diabetes (Gaikwad AB et al., 2022).

Ostrzeżenie

Toxicity: Standard Handling (A)

Inne uwagi

Ozcan, U., et al. 2006. Science313, 1137.
Miyake, H., et al. 1999. Dig. Dis. Sci.44, 197.
Eto, T. and Tompkins, R.K. 1985. Am. J. Surg.150, 564.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

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Odwiedź Bibliotekę dokumentów

Crystal L Kraft et al.
Oncotarget, 8(61), 102923-102933 (2017-12-22)
Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential underlie the necessity for tight homeostatic regulation of
Yaqin Chen et al.
PloS one, 8(10), e81379-e81379 (2013-11-28)
Adipocytes behave as a rich source of adipokines, which may be the link between obesity and its complications. Endoplasmic reticulum (ER) stress in adipocytes can modulate adipokines secretion. The aim of this study is to evaluate the effect of oxidized
Xiaoling Li et al.
The Journal of biological chemistry, 293(14), 5160-5171 (2018-02-25)
The liver is a major organ in lipid metabolism, and its malfunction leads to various diseases. Nonalcoholic fatty liver disease, the most common chronic liver disorder in developed countries, is characterized by the abnormal retention of excess lipid within hepatocytes
Emily M Nakada et al.
JCI insight, 4(9) (2019-05-03)
Conjugated bile acids (CBAs), such as tauroursodeoxycholic acid (TUDCA), are known to resolve the inflammatory and unfolded protein response (UPR) in inflammatory diseases, such as asthma. Whether CBAs exert their beneficial effects on allergic airway responses via 1 arm or
Isabel Castro et al.
Rheumatology (Oxford, England), 59(4), 742-753 (2019-08-05)
Xerostomia in SS patients has been associated with low quality and quantity of salivary mucins, which are fundamental for the hydration and protection of the oral mucosa. The aim of this study was to evaluate if cytokines induce aberrant mucin
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