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Sigma-Aldrich

Protease Inhibitor Cocktail Set V, EDTA-Free

A cocktail of four protease inhibitors for the inhibition of serine, cysteine, but not metalloproteases.

Synonim(y):

EDTA free Protease inhibitor

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About This Item

Kod UNSPSC:
12352200

Poziom jakości

Postać

lyophilized

producent / nazwa handlowa

Calbiochem®

warunki przechowywania

OK to freeze
desiccated (hygroscopic)

Warunki transportu

wet ice

temp. przechowywania

−20°C

Opis ogólny

A cocktail of four protease inhibitors for the inhibition of serine, cysteine, but not metalloproteases. Recommended for use with mammalian cell lysates and tissue extracts. Provided as a single vial or a set of 10 vials. When reconstituted each vial contains a 100X stock solutions. When diluted to 1X the cocktail contains the following components:
A cocktail of four protease inhibitors for the inhibition of serine, cysteine, but not metalloproteases. Reconstitute each vial with 1 ml H2O to obtain a 100X stock solution. 1X stock solution contains 500 µM AEBSF, HCl (Cat. No. 101500), 150 nM Aprotinin (Cat. No. 616370), 1 µM E-64 (Cat. No. 324890), and 1 µM Leupeptin Hemisulfate (Cat. No. 108975). Supplied with a data sheet.

Specyficzność

Inhibits serine proteases, cysteine proteases. Does not inhibit metalloproteases.

Działania biochem./fizjol.

Cell permeable: no
Primary Target
Serine and cysteine proteases, but not metalloproteases
Product does not compete with ATP.
Reversible: no

Ostrzeżenie

Toxicity: Standard Handling (A)

Rekonstytucja

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Reconstitute each vial with 1 ml H₂O to obtain a 100X stock solution.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
This page may contain text that has been machine translated.

Piktogramy

Corrosion

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

Klasyfikacja zagrożeń

Eye Dam. 1 - Skin Corr. 1A

Kod klasy składowania

8A - Combustible, corrosive hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Mario Lebendiker et al.
Methods in molecular biology (Clifton, N.J.), 1485, 257-273 (2016-10-13)
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Chinyere Agbaegbu Iweka et al.
Journal of neurochemistry, 157(3), 494-507 (2020-12-16)
Phospholipid Phosphatase-Related Protein Type 1 (PLPPR1) is a member of a family of lipid phosphatase related proteins, integral membrane proteins characterized by six transmembrane domains. This family of proteins is enriched in the brain and recent data indicate potential pleiotropic
Keane K Y Lai et al.
Cancers, 13(6) (2021-04-04)
Differential usage of Kat3 coactivators, CBP and p300, by β-catenin is a fundamental regulatory mechanism in stem cell maintenance and initiation of differentiation and repair. Based upon our earlier pharmacologic studies, p300 serine 89 (S89) is critical for controlling differential
Qiongyu Li et al.
Nature protocols, 15(8), 2668-2704 (2020-07-19)
The glycocalyx comprises glycosylated proteins and lipids and fcorms the outermost layer of cells. It is involved in fundamental inter- and intracellular processes, including non-self-cell and self-cell recognition, cell signaling, cellular structure maintenance, and immune protection. Characterization of the glycocalyx
Jonathan L Chen et al.
Journal of the American Chemical Society, 142(19), 8706-8727 (2020-05-05)
Approximately 95% of human genes are alternatively spliced, and aberrant splicing events can cause disease. One pre-mRNA that is alternatively spliced and linked to neurodegenerative diseases is tau (microtubule-associated protein tau), which can cause frontotemporal dementia and parkinsonism linked to

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