362339

Glyco-SNAP-2

A water-soluble nitric oxide (NO) donor that exhibits greater stability (t1/2 = 27 hours) than that of SNAP.

• Synonim(y): Glyco-SNAP-2, N-(2-Deoxy-α,β-D-glucopyranose-2-)-N²-acetyl-S-nitroso-D,L-penicillaminamide
• Wzór empiryczny (zapis Hilla): C₁₃H₂₃N₃O₈S
• Numer CAS: 188849-82-3
• Masa cząsteczkowa: 381.40
• Kod UNSPSC: 12352200
• Identyfikator substancji w PubChem: 3413551
• NACRES: NA.77

Właściwości

• Poziom jakości: 100
• Próba: ≥95% (HPLC)
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; protect from light
• kolor: green
• rozpuszczalność: aqueous buffer: >100 mg/mL; methanol: soluble; water: soluble
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• ciąg SMILES: CC(=O)NC(C(=O)NC1C(C(C(OC1O)CO)O)O)C(C)(C)SN=O

Opis

Opis ogólny

A nitric oxide donor that exhibits greater stability than SNAP in aqueous medium, in both the presence and absence of EDTA. The half life of Glyco-SNAP-2 in aqueous medium is 27.4 h at room temperature, in the absence of EDTA, compared to 10.3 h for SNAP. The compound consists of a S-nitroso-N-acetylpencilamine moiety, which acts as a NO-donor, and a sugar fragment, which provides the desired hydrophobicity.

A water-soluble nitric oxide (NO) donor that exhibits greater stability (t_½ = 27 hours) than that of SNAP. Exhibits properties similar to those of Glyco-SNAP-1 (Cat. No. 362338).

Działania biochem./fizjol.

Cell permeable: no

Primary Target
Water-soluble nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

Ostrzeżenie

Toxicity: Standard Handling (A)

Rekonstytucja

Unstable in solution; reconstitute just prior to use.

Inne uwagi

Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable