200100

Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside

≥98% (TLC), solid, O-linked glycosylation inhibitor, Calbiochem^®

• Synonim(y): Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside, Benzyl-α-GalNAc
• Wzór empiryczny (zapis Hilla): C₁₅H₂₁NO₆
• Numer CAS: 3554-93-6
• Masa cząsteczkowa: 311.33
• Numer MDL: MFCD00057920
• Kod UNSPSC: 12352200

Właściwości

• product name: Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside, Used as an inhibitor of O-linked glycosylation in a variety of cell lines.
• Poziom jakości: 100
• Próba: ≥98% (TLC)
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• kolor: off-white
• rozpuszczalność: hot ethanol: 1 mg/mL; DMSO: 100 mg/mL
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• ciąg SMILES: CC(N[C@H]([C@H]([C@H]1O)O)[C@H](O[C@@H]1CO)OCC2=CC=CC=C2)=O
• InChI: 1S/C15H21NO6/c1-9(18)16-12-14(20)13(19)11(7-17)22-15(12)21-8-10-5-3-2-4-6-10/h2-6,11-15,17,19-20H,7-8H2,1H3,(H,16,18)/t11-,12-,13+,14-,15+/m1/s1
• Klucz InChI: SKOZFDIGKDPQBO-QMIVOQANSA-N

Opis

Opis ogólny

Used as an inhibitor of O-linked glycosylation in a variety of cell lines. Also inhibits 2,3(O)-sialyltransferase and disrupts glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.

Used as an inhibitor of O-linked glycosylation in a variety of cell lines. It has also been used to inhibit 2,3(O)-sialyltransferase and disrupt glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.

Działania biochem./fizjol.

Cell permeable: no

Primary Target
o-linked glycosylation

Product does not compete with ATP.

Reversible: no

Ostrzeżenie

Toxicity: Standard Handling (A)

Inne uwagi

Huet, G., et al. 1998. J. Cell Biol. 141, 1311.
Kuan, S.-F., et al. 1989. J. Biol. Chem. 264, 19271.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable