19-148
Bafilomycin A1
Synonim(y):
Bafilomycin A
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About This Item
Polecane produkty
opis
Bafilomycin A1 is a specific potent inhibitor of vacuolar-type H+-ATPases, and blocks lysosomal cholesterol transport in macrophages.
Poziom jakości
producent / nazwa handlowa
Upstate®
metody
activity assay: suitable (kinase)
temp. przechowywania
−20°C
Zastosowanie
Bafilomycin A1 has been used:
- as an autophagy inhibitor to study its effect on traumatic brain injury (TBI)-induced cell death and lesions in mice
- to treat neurons for pH luorin assays to measure endocytosis during synaptic activity
- to block autophagy in mouse embryonic fibroblasts
Działania biochem./fizjol.
Inhibitor Type: Kinase
Postać fizyczna
C35H58O9
Przechowywanie i stabilność
3 years at -20°C
Informacje prawne
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
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