1.03669

Glycine

granulated, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP

• Synonim(y): Gly, Aminoacetic acid, Aminoethanoic acid, Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Wzór liniowy: NH₂CH₂COOH
• Numer CAS: 56-40-6
• Masa cząsteczkowa: 75.07
• Beilstein: 635782
• Numer MDL: MFCD00008131
• Kod UNSPSC: 12352209
• Numer indeksu EC: 200-272-2

Właściwości

• agency: BP; ChP; JP; Ph. Eur.; USP
• Poziom jakości: 500
• ciśnienie pary: 0.0000171 Pa ( 25 °C)
• opis: granulated EMPROVE^® EXPERT Ph.Eur.,BP,JP,USP
• linia produktu: EMPROVE^® EXPERT
• Próba: 99.0-101.0% (calculated on dried substance, perchloric acid titration)
• Formularz: granular
• metody: inhibition assay: suitable
• pH: 5.9-6.4 (20 °C, 50 g/L in H₂O)
• pKa (25°C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• gęstość: 1.161 g/cm³ at 20 °C
• Zastosowanie: liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical
• temp. przechowywania: 2-30°C
• ciąg SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Klucz InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N

Opis

Opis ogólny

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing processes and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, granulated glycine is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Zastosowanie

Glycine in general is widely used in the biopharma industry as a stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine granulated Emprove^® Expert is especially suitable for high-risk applications.

Działania biochem./fizjol.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Informacje prawne

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable