05-1527

Anti-eIF4A3 Antibody, clone 3F1

clone 3 F 1, from mouse

• Synonim(y): ATP-dependent RNA helicase DDX48, ATP-dependent RNA helicase eIF4A-3, DEAD (Asp-Glu-Ala-Asp) box polypeptide 48, DEAD box protein 48, Eukaryotic initiation factor 4A-like NUK-34, Eukaryotic translation initiation factor 4A isoform 3, Nuclear matrix prote
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified antibody
• rodzaj przeciwciała: primary antibodies
• klon: 3 F 1, monoclonal
• reaktywność gatunkowa: human
• reaktywność gatunkowa (przewidywana na podstawie homologii): mouse
• metody: immunocytochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_055555.1
• numer dostępu UniProt: P38919
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... EIF4A3(9775)

Opis

Opis ogólny

Eukaryotic translation initiation factor 4A, isoform 3, also known as eIF4A3, is a member of the DEAD box protein family. DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). This family of proteins are putative RNA helicases and are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. eIF4A3 is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Specyficzność

This antibody recognizes eIF4A3.

Immunogen

Epitope: Unknown

GST-tagged recombinant protein corresponding to human eIF4A3.

Zastosowanie

Immunoprecipitation: Reported by independent laboratory using representative lot.
Immunocytochemistry: Reported by independent laboratory using representative lot.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Use Anti-eIF4A3 Antibody, clone 3F1 (mouse monoclonal antibody) validated in WB, IP, ICC to detect eIF4A3 also known as ATP-dependent RNA helicase DDX48, Eukaryotic translation initiation factor 4A isoform 3.

Jakość

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected eIF4A3 on 10 µg in HeLa cell lysate.

Opis wartości docelowych

47 kDa

Postać fizyczna

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
HeLa cell lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable