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P-075

Supelco

Primidone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Wzór empiryczny (zapis Hilla):
C12H14N2O2
Numer CAS:
125-33-7
Masa cząsteczkowa:
218.25
Numer WE:
200-659-6
Kod UNSPSC:
41116107
NACRES:
NA.24

klasa czystości

certified reference material

Poziom jakości

300

Formularz

liquid

Właściwości

Snap-N-Spike®/Snap-N-Shoot®

opakowanie

ampule of 1 mL

producent / nazwa handlowa

Cerilliant®

stężenie

1.0 mg/mL in methanol

metody

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Zastosowanie

forensics and toxicology

Format

single component solution

temp. przechowywania

−20°C

ciąg SMILES

CCC1(C(=O)NCNC1=O)c2ccccc2

InChI

1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)

Klucz InChI

DQMZLTXERSFNPB-UHFFFAOYSA-N

informacje o genach

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Opis ogólny

Primidone, marketed as the barbiturate Mysoline®, Prysoline, or Liskantin®, is an anticonvulsant used in the treatment of partial and generalized seizures. This Certified Spiking Solution® is suitable for use in LC/MS or GC/MS applications in clinical toxicology or therapeutic drug monitoring to ensure patients remain within the drug′s therapeutic range.

Zastosowanie


  • LC-MS/MS-Based Quantification of 9 Antiepileptic Drugs From a Dried Sample Spot Device.: This study utilizes PrimiDonesolution as a reagent in the development of a high-throughput method for quantifying antiepileptic drugs. PrimiDone is critical for accurate measurements in biochemical and pharmacological research, especially in epilepsy studies (DUrso et al., 2019).

  • Application of packed column supercritical fluid chromatography to the simultaneous determination of seven anticonvulsant drugs.: The research demonstrates the use of PrimiDonesolution in supercritical fluid chromatography to simultaneously determine multiple anticonvulsants, highlighting its importance as a stable reagent for laboratory use and anticonvulsant research (Bhoir et al., 1999).

  • The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. I. The influence of administration vehicles.: This paper discusses the use of PrimiDonesolution as a vehicle in laboratory evaluations of anticonvulsant drugs, emphasizing its stability and reliability for pharmacological experimentation and neurological disorder research (Loscher et al., 1990).

  • Simple GLC analysis of anticonvulsant drugs in commercial dosage forms.: This study utilizes PrimiDonesolution in gas-liquid chromatography to analyze commercial anticonvulsant drugs, underlining its role as a high-purity reagent for biochemical studies and anticonvulsant research (Watson et al., 1978).

  • Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.: PrimiDonesolution is used in a rapid micromethod for serum analysis of anticonvulsants, demonstrating its utility as a PrimiDone reagent for anticonvulsant research and in vitro biochemical studies (Soldin and Hill, 1976).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Liskantin is a registered trademark of Desitin Arzneimittel GmbH
Mysoline is a registered trademark of Valeant Pharmaceuticals North America LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
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Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H225,H301 + H311 + H331,H370

Klasyfikacja zagrożeń

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organy docelowe

Eyes,Central nervous system

Kod klasy składowania

3 - Flammable liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

49.5 °F - closed cup

Temperatura zapłonu (°C)

9.7 °C - closed cup

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Certyfikaty analizy (CoA)

Lot/Batch Number

Przepraszamy, ale COA dla tego produktu nie jest aktualnie dostępny online.

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Odwiedź Bibliotekę dokumentów

B Rezaei et al.
Talanta, 79(3), 669-675 (2009-07-07)
Application of electrospray ionization ion mobility spectrometry (ESI-IMS) as the detection technique for separation method based on molecular imprinted polymer (MIP) was investigated and evaluated. The method is exhaustively validated, including sensitivity, selectivity, recovery, reproducibility, and column capacity. The linear
Susheela Rani et al.
Journal of separation science, 35(3), 359-366 (2012-01-20)
A method for the simultaneous determination of the antiepileptic drugs, phenobarbital (PHB), phenytoin (PTN), carbamazepine (CBZ), primidone (PRM) and oxcarbazepine (OXC) in human plasma and urine samples by using micro-extraction in a packed syringe as the sample preparation method connected
Feng Chen et al.
Environmental pollution (Barking, Essex : 1987), 159(6), 1490-1498 (2011-04-12)
This study investigated the occurrence of 43 emerging contaminants including 9 endocrine-disrupting chemicals and 34 pharmaceuticals in three sites in Hebei Province, north China. Each site has a wastewater irrigated plot and a separate groundwater irrigated plot for comparison purpose.
Christopher G Favilla et al.
Parkinsonism & related disorders, 19(2), 171-175 (2012-10-16)
Many essential tremor patients continue to require tremor suppressing medications following deep brain stimulation. The true incidence of medication usage in the years following surgery remains unclear, and the use of medications has not been included in the post-operative analyses
Joan Oppenheimer et al.
Water research, 45(13), 4019-4027 (2011-06-15)
Urban watersheds are susceptible to numerous pollutant sources and the identification of source-specific indicators can provide a beneficial tool in the identification and control of input loads, often times needed for a water body to achieve designated beneficial uses. Differentiation
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