B-901

Buprenorphine-D₄ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Wzór empiryczny (zapis Hilla): C₂₉H₃₇NO₄D₄
• Numer CAS: 136781-89-0
• Masa cząsteczkowa: 471.66
• Numer WE: 200-659-6
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material
• Poziom jakości: 300
• Postać: liquid
• Właściwości: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• opakowanie: ampule of 1 mL
• producent / nazwa handlowa: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• stężenie: 100 μg/mL in methanol
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Zastosowanie: forensics and toxicology
• format: single component solution
• temp. przechowywania: 2-8°C
• ciąg SMILES: [2H]C1([2H])CC1C([2H])([2H])N2CC[C@]34[C@H]5Oc6c(O)ccc(C[C@@H]2[C@]37CC[C@@]5(OC)[C@H](C7)[C@](C)(O)C(C)(C)C)c46
• InChI: 1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1/i6D2,16D2/t17?,20-,21-,24-,26+,27-,28+,29-
• Klucz InChI: RMRJXGBAOAMLHD-UHGBJPCQSA-N

Opis

Opis ogólny

An internal standard suitable for buprenorphine testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, pain prescription monitoring, urine drug testing, or forensic analysis. Buprenorphine is a semi-synthetic opiate used in the treatment of moderate acute pain and opioid addiction. The drug is sold under numerous trade names such as Suboxone^®, Subutex^®, and Temgesic.

Zastosowanie

• Determination of buprenorphine and norbuprenorphine in urine and hair by gas chromatography-mass spectrometry - This pivotal study utilizes Buprenorphine-D₄ as an internal standard to enhance the analytical accuracy of buprenorphine and its metabolite norbuprenorphine in biological samples, crucial for opioid pharmacokinetics study and drug monitoring (Vincent et al., 1999).


• HPLC-MS for the determination of sildenafil citrate (Viagra) in biological fluids. Application to the salivary excretion of sildenafil after oral intake - Although this study primarily focuses on sildenafil, the methodology involving high-performance liquid chromatography coupled with mass spectrometry (HPLC-MS) where Buprenorphine-D₄ can be utilized as an internal standard demonstrates its broader application potential in drug metabolism and pharmacokinetic research, especially in studies involving complex biological matrices (Tracqui et al., 2003).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Suboxone is a registered trademark of RB Pharmaceuticals Limited

Subutex is a registered trademark of RB Pharmaceuticals Limited

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H225,H301 + H311 + H331,H370
• Zwroty wskazujące środki ostrożności: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Klasyfikacja zagrożeń: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organy docelowe: Eyes,Central nervous system
• Kod klasy składowania: 3 - Flammable liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): 49.5 °F - closed cup
• Temperatura zapłonu (°C): 9.7 °C - closed cup