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4,4,4-Trifluoro-1-(2-furyl)-1,3-butanedione
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About This Item
Polecane produkty
Poziom jakości
Próba
99%
Postać
liquid
współczynnik refrakcji
n20/D 1.528 (lit.)
tw
203 °C (lit.)
mp
19-21 °C (lit.)
gęstość
1.391 g/mL at 25 °C (lit.)
temp. przechowywania
2-8°C
ciąg SMILES
FC(F)(F)C(=O)CC(=O)c1ccco1
InChI
1S/C8H5F3O3/c9-8(10,11)7(13)4-5(12)6-2-1-3-14-6/h1-3H,4H2
Klucz InChI
OWLPCALGCHDBCN-UHFFFAOYSA-N
Opis ogólny
4,4,4-Trifluoro-1-(2-furyl)-1,3-butanedione (furoyltrifluoroacetone, FTFA) is a β-diketone. Its cytotoxic activity against human cultured tumor and normal cells has been evaluated. Reports suggest that 4,4,4-trifluoro-1-(2-furyl)-1,3-butanedione partially inhibits the oxidation of ferrocyanide in ETP (electron transport particles) isolated from beef heart mitochondria. Its reaction with N,N,N′,N′-tetramethylalkyl diamines to form ionic adducts has been investigated. The conformational analysis of the enol and keto form of FTFA has been reported.
Zastosowanie
4,4,4-Trifluoro-1-(2-furyl)-1,3-butanedione (tfa) may be used in the following studies:
- As capping ligand in the synthesis of [Eu(tfa)3]2bpm complexes (bpm=2,2′-bipyrimidine).
- As reagent in the multistep synthesis of [13CD2]benzylamine.
- As reagent in the synthesis of 3-trifluoromethyl-2-arylcarbonylquinoxaline 1,4-di-N-oxide derivatives by reacting with corresponding benzofurazan oxides.
- In the efficient syntheses of perfluoroalkyl substituted azoles.
- Synthesis of 2-arylcarbonyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
188.6 °F - closed cup
Temperatura zapłonu (°C)
87 °C - closed cup
Środki ochrony indywidualnej
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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