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Merck

GRIA1

glutamate receptor, ionotropic, AMPA 1

Synonimy:
GLUH1, GLUR1, GLURA, GluA1, HBGR1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2890) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14799) glutamate receptor, ionotropic, AMPA1 (alpha 1)
  • Rat(50592) glutamate receptor, ionotropic, AMPA 1
  • sheep(443271) glutamate receptor, ionotropic, AMPA 1
  • Domestic Rabbit(100348217) glutamate receptor, ionotropic, AMPA 1
  • domestic guinea pig(100727046) glutamate receptor, ionotropic, AMPA 1
  • naked mole-rat(101724828) glutamate receptor, ionotropic, AMPA 1
  • chicken(414893) glutamate receptor, ionotropic, AMPA 1
  • cow(529618) glutamate receptor, ionotropic, AMPA 1
  • Horse(100060020) glutamate receptor, ionotropic, AMPA 1
  • domestic cat(101097621) glutamate receptor, ionotropic, AMPA 1
  • dog(489168) glutamate receptor, ionotropic, AMPA 1

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
ATPA, solid,
Gatunek
human, rat
2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide, ≥98% (HPLC), solid,
Gatunek
human
Cyclothiazide, ,
Gatunek
human, rat
Quisqualic acid, powder,
Gatunek
rat
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Gatunek
human, rat

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
CX546, ≥98% (HPLC), solid,
Gatunek
human
Piracetam, ,
Gatunek
human, rat
Cyclothiazide, ,
Gatunek
human, rat
Diazoxide, ,
Gatunek
rat, mouse, human
Kainic acid monohydrate, ≥99% (TLC),
Gatunek
human, mouse, rat

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
2,3-Pyridinedicarboxylic acid, 99%,
Gatunek
rat
2,3-Dihydroxyquinoxaline, 98%,
Gatunek
rat
ATPA, solid,
Gatunek
human, rat
GYKI 52466 hydrochloride, solid,
Gatunek
human
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Gatunek
rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-GluR1 (pSer849) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
Anti-phospho-GluR1 (Ser831) Antibody, clone N453, rabbit monoclonal, culture supernatant, clone N453, Upstate®,
Reaktywność gatunkowa
chicken, human, mouse, rat
Zastosowanie
western blot
Anti-GluR1 Antibody, clone C3T, rabbit monoclonal, culture supernatant, clone C3T, Upstate®,
Reaktywność gatunkowa
chimpanzee, human, mouse, rat
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-pan-AMPA receptor (GluR1-4), clone 2D8 Antibody, clone 2D8, from mouse,
Reaktywność gatunkowa
human, rat
Zastosowanie
ELISA
electron microscopy

immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-GRIA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Cyclothiazide, ,
Gatunek
human, rat
Kynurenic acid, ≥98%,
Gatunek
rat, human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
Quisqualic acid, powder,
Gatunek
rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
ATPA, solid,
Gatunek
human, rat
Cyclothiazide, ,
Gatunek
human, rat
(±)-AMPA, solid,
Gatunek
rat
Kainic acid monohydrate, ≥99% (TLC),
Gatunek
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Gatunek
rat, human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human GRIA1,
Gatunek
human