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CDK2

cyclin-dependent kinase 2

Synonimy:
p33(CDK2)
Gatunek:
Human CDK2 (1017), Mouse Cdk2 (12566), Rat Cdk2 (362817), Zebrafish cdk2 (406715), cow CDK2 (519217), chicken CDK2 (100529062), dog CDK2 (606931), domestic cat CDK2 (101093368), domestic guinea pig Cdk2 (100714324), naked mole-rat Cdk2 (101725353) ...Więcej
Identyfikator UniProtKB:
P24941, A8K7C6, O75100
Identyfikator genu:
  • Human(1017) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(12566) cyclin-dependent kinase 2
  • Rat(362817) cyclin dependent kinase 2
  • Zebrafish(406715) cyclin-dependent kinase 2
  • cow(519217) cyclin-dependent kinase 2
  • chicken(100529062) cyclin-dependent kinase 2
  • dog(606931) cyclin-dependent kinase 2
  • domestic cat(101093368) cyclin-dependent kinase 2
  • domestic guinea pig(100714324) cyclin-dependent kinase 2
  • naked mole-rat(101725353) cyclin-dependent kinase 2
  • Goat(100860751) cyclin-dependent kinase 2
  • sheep(100216433) cyclin-dependent kinase 2
  • Domestic Rabbit(100134865) cyclin-dependent kinase 2

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4504362
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
SAB4503907
Anti-phospho-CDK1/CDC2 (pThr14) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
western blot
05-596
Przeciwciało anty-Cdk2, klon AN4.3, clone AN4.3, Upstate®, from mouse,
Reaktywność gatunkowa
xenopus, human, mouse
Zastosowanie
immunoprecipitation (IP)
western blot
AV03006
Anti-CDK2 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
bovine, goat, human, mouse, rabbit, rat, sheep
Zastosowanie
immunohistochemistry
western blot
SAB4300388
Anti-CDK2 (Ab-160) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
P0453
Piceatannol, powder,
Gatunek
human
T7165
Tyrphostin 23, ≥98%,
Gatunek
human
N4286
NU2058, >98% (HPLC),
Gatunek
human
T7665
Tyrphostin 51, ≥98%,
Gatunek
human
363057
6-O-Methylguanine, 97%,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
14-450-M
Białko Cdk1/cykliny B, aktywne, 10 µg, Active, C-terminal His6-tagged human full length Cdk1 & N-terminal GST-tagged human full length Cyclin B, for use in Kinase Assays.,
Gatunek
human
14-475-M
Białko Cdk2/Cyklina E, aktywne, 10 µg, Active complex of recombinant full length human Cdk2 containing a C-terminal His6-tag & recombinant full-length human Cyclin E containing an N-terminal GST-tag. For use in Kinase Assays.,
Gatunek
human
C0495
CDK2/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
SRP5010
CDK2/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
23-024-M
Kompleks białkowy p27, aktywowany, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU061761
MISSION® esiRNA, targeting human CDK2,
Gatunek
human
EMU085451
MISSION® esiRNA, targeting mouse Cdk2,
Gatunek
mouse