ADRA2B
adrenoceptor alpha 2B
Synonimy:
ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR
Gatunek:
Human ADRA2B (151), Mouse Adra2b (11552), Rat Adra2b (24174), Zebrafish adra2b (266751), dog ADRA2B (611658), cow ADRA2B (516422), Horse ADRA2B (100051684), chicken ADRA2B (427631), domestic cat ADRA2B (101090432), sheep ADRA2B (100170318) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(151) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. This intronless gene encodes the alpha2B subtype, which was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. [provided by RefSeq, Aug 2011]
- Mouse(11552) adrenergic receptor, alpha 2b
- Rat(24174) adrenoceptor alpha 2B
- Zebrafish(266751) adrenergic, alpha-2B-, receptor
- dog(611658) adrenergic, alpha-2B-, receptor
- cow(516422) adrenergic, alpha-2B-, receptor
- Horse(100051684) adrenoceptor alpha 2B
- chicken(427631) adrenergic, alpha-2B-, receptor
- domestic cat(101090432) adrenoceptor alpha 2B
- sheep(100170318) adrenoceptor alpha 2B
- naked mole-rat(101701692) adrenoceptor alpha 2B
- domestic guinea pig(100135476) adrenergic receptor, alpha 2b
- domestic guinea pig(100727868) adrenoceptor alpha 2B
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Small Molecule - Antagonist
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Gatunek
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Antibodies
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Zastosowanie
Receptor adrenergiczny anty-alfa 2b, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Anty-ADRA2B, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty-ADRA2B, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Small Molecule - Blocker
Small Molecule - Mixed Agonist/Antagonist
esiRNA
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